Benita S Katzenellenbogen

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Research Output

Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands

Minutolo, F., Bertini, S., Martinelli, A., Ortore, G., Placanica, G., Prota, G., Rapposelli, S., Tuccinardi, T., Sheng, S., Carlson, K. E., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Macchia, M., Jun 24 2006, In : Arkivoc. 2006, 8, p. 83-94 12 p.

Research output: Contribution to journalArticle

Science Signaling podcast for 24 May 2016: Designer estrogens

Katzenellenbogen, B. S., Katzenellenbogen, J. A., Madak-Erdogan, Z. & Van hook, A. M., May 24 2016, In : Science Signaling. 9, 429, pc13.

Research output: Contribution to journalReview article

Selective Estrogen Receptor Modulators: Discrimination of Agonistic versus Antagonistic Activities by Gene Expression Profiling in Breast Cancer Cells

Frasor, J., Stossi, F., Danes, J. M., Komm, B., Lyttle, C. R. & Katzenellenbogen, B. S., Feb 15 2004, In : Cancer Research. 64, 4, p. 1522-1533 12 p.

Research output: Contribution to journalArticle

Selective Nonnuclear Estrogen Receptor Activation Decreases Stroke Severity and Promotes Functional Recovery in Female Mice

Selvaraj, U. M., Zuurbier, K. R., Whoolery, C. W., Plautz, E. J., Chambliss, K. L., Kong, X., Zhang, S., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Mineo, C., Shaul, P. W. & Stowe, A. M., Jan 1 2018, In : Endocrinology. 159, 11, p. 3848-3859 12 p.

Research output: Contribution to journalArticle

Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain

Acevedo, M. L., Lee, K. C., Stender, J. D., Katzenellenbogen, B. S. & Kraus, W. L., Mar 5 2004, In : Molecular cell. 13, 5, p. 725-738 14 p.

Research output: Contribution to journalArticle

Some properties of silkmoth moulting gel and moulting fluid

Katzenellenbogen, B. S. & Kafatos, F. C., Dec 1970, In : Journal of insect physiology. 16, 12, p. 2241-2256 16 p.

Research output: Contribution to journalArticle

Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination

Poitelon, Y., Bogni, S., Matafora, V., Della-Flora Nunes, G., Hurley, E., Ghidinelli, M., Katzenellenbogen, B. S., Taveggia, C., Silvestri, N., Bachi, A., Sannino, A., Wrabetz, L. & Feltri, M. L., Sep 18 2015, In : Nature communications. 6, 8303.

Research output: Contribution to journalArticle

Stilbestrols and stilbestrol derivatives: Estrogenic potency and temporal relationships between estrogen receptor binding and uterine growth

Katzenellenbogen, B. S., Iwamoto, H. S., Heiman, D. F., Lan, N. C. & Katzenellenbogen, J. A., Jan 1 1978, In : Molecular and Cellular Endocrinology. 10, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

Structural Analysis of Covalently Labeled Estrogen Receptors by Limited Proteolysis and Monoclonal Antibody Reactivity

Katzenellenbogen, B. S., Greene, G. L., Elliston, J. F., Monsma, F. J., Springer, P. A. & Ziegler, Y. S., Jan 1 1987, In : Biochemistry. 26, 8, p. 2364-2373 10 p.

Research output: Contribution to journalArticle

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

Shiau, A. K., Barstad, D., Radek, J. T., Meyers, M. J., Nettles, K. W., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Agard, D. A. & Greene, G. L., May 13 2002, In : Nature Structural Biology. 9, 5, p. 359-364 6 p.

Research output: Contribution to journalArticle

Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors

Zhao, Y., Laws, M. J., Guillen, V. S., Ziegler, Y., Min, J., Sharma, A., Kim, S. H., Chu, D., Park, B. H., Oesterreich, S., Mao, C., Shapiro, D. J., Nettles, K. W., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 15 2017, In : Cancer Research. 77, 20, p. 5602-5613 12 p.

Research output: Contribution to journalArticle

Structural underpinnings of oestrogen receptor mutations in endocrine therapy resistance

Katzenellenbogen, J. A., Mayne, C. G., Katzenellenbogen, B. S., Greene, G. L. & Chandarlapaty, S., Jun 1 2018, In : Nature Reviews Cancer. 18, 6, p. 377-388 12 p.

Research output: Contribution to journalReview article

Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles

Katzenellenbogen, B. S., Sun, J., Harrington, W. R., Kraichely, D. M., Ganessunker, D. & Katzenellenbogen, J. A., Jan 1 2001, In : Annals of the New York Academy of Sciences. 949, p. 6-15 10 p.

Research output: Contribution to journalArticle

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains

Zhou, H. B., Sheng, S., Compton, D. R., Kim, Y., Joachimiak, A., Sharma, S., Carlson, K. E., Katzenellenbogen, B. S., Nettles, K. W., Greene, G. L. & Katzenellenbogen, J. A., Jan 25 2007, In : Journal of Medicinal Chemistry. 50, 2, p. 399-403 5 p.

Research output: Contribution to journalArticle

Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds

Ziegler, Y., Laws, M. J., Sanabria Guillen, V., Kim, S. H., Dey, P., Smith, B. P., Gong, P., Bindman, N., Zhao, Y., Carlson, K., Yasuda, M. A., Singh, D., Li, Z., El-Ashry, D., Madak-Erdogan, Z., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Dec 1 2019, In : npj Breast Cancer. 5, 1, 45.

Research output: Contribution to journalArticle

Open Access

Synergistic activation of the serotonin-1A receptor by nuclear factor-κB and estrogen

Wissink, S., Van Der Burg, B., Katzenellenbogen, B. S. & Van Der Saag, P. T., May 1 2001, In : Molecular Endocrinology. 15, 4, p. 543-552 10 p.

Research output: Contribution to journalArticle

Synthesis and biological evaluation of a novel series of furans: Ligands selective for estrogen receptor α

Mortensen, D. S., Rodriguez, A. L., Carlson, K. E., Sun, J., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 8 2001, In : Journal of Medicinal Chemistry. 44, 23, p. 3838-3848 11 p.

Research output: Contribution to journalArticle

Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: Estrogen antagonists of unusual structure

Zhou, H. B., Comninos, J. S., Stossi, F., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Nov 17 2005, In : Journal of Medicinal Chemistry. 48, 23, p. 7261-7274 14 p.

Research output: Contribution to journalArticle

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen

Robertson, D. W., Katzenellenbogen, J. A., Long, D. J., Rorke, E. A. & Katzenellenbogen, B. S., Jan 1982, In : Journal of Steroid Biochemistry. 16, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Tamoxifen aziridines: Effective inactivators of the estrogen receptor

Robertson, D. W., Wei, L. L., Hayes, J. R., Carlson, K. E., Katzenellenbogen, J. A. & Katzenellenbogen, B. S., Oct 1981, In : Endocrinology. 109, 4, p. 1298-1300 3 p.

Research output: Contribution to journalArticle

Tamoxifen downregulation of miR-451 increases 14-3-3ζ and promotes breast cancer cell survival and endocrine resistance

Bergamaschi, A. & Katzenellenbogen, B. S., Jan 5 2012, In : Oncogene. 31, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells

Smirnova, N. F., Fontaine, C., Buscato, M., Lupieri, A., Vinel, A., Valera, M. C., Guillaume, M., Malet, N., Foidart, J. M., Raymond-Letron, I., Lenfant, F., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Laffargue, M. & Arnal, J. F., Oct 9 2015, In : Circulation Research. 117, 9, p. 770-777 8 p.

Research output: Contribution to journalArticle

The androgen derivative 5α-androstane-3β,17β-diol inhibits prostate cancer cell migration through activation of the estrogen receptor β subtype

Guerini, V., Sau, D., Scaccianoce, E., Rusmini, P., Ciana, P., Maggi, A., Martini, P. G. V., Katzenellenbogen, B. S., Martini, L., Motta, M. & Poletti, A., Jun 15 2005, In : Cancer Research. 65, 12, p. 5445-5453 9 p.

Research output: Contribution to journalArticle

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro

Aumsuwan, P., Khan, S. I., Khan, I. A., Ali, Z., Avula, B., Walker, L. A., Shariat-Madar, Z., Helferich, W. G., Katzenellenbogen, B. S. & Dasmahapatra, A. K., Feb 1 2016, In : Archives of Biochemistry and Biophysics. 591, p. 98-110 13 p.

Research output: Contribution to journalArticle

The Capacity of the Antiestrogen CI-628 to Activate the Estrogen Receptor in Vitro

De Boer, W. D., Notides, A. C., Katzenellenbogen, B. S., Hayes, J. R. & Katzenellenbogen, J. A., Jan 1981, In : Endocrinology. 108, 1, p. 206-212 7 p.

Research output: Contribution to journalArticle

The coregulator, repressor of estrogen receptor activity (REA), is a crucial regulator of the timing and magnitude of uterine decidualization

Zhao, Y., Park, S., Bagchi, M. K., Taylor, R. N. & Katzenellenbogen, B. S., Mar 1 2013, In : Endocrinology. 154, 3, p. 1349-1360 12 p.

Research output: Contribution to journalArticle

The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones

Bowe, J., Li, X. F., Sugden, D., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & O'Byrne, K. T., Feb 1 2003, In : Journal of Neuroendocrinology. 15, 2, p. 105-108 4 p.

Research output: Contribution to journalArticle

The estrogen receptor: A structure-based approach to the design of new specific hormone-receptor combinations

Tedesco, R., Thomas, J. A., Katzenellenbogen, B. S. & Katzenellenbogen, J. A., Apr 25 2001, In : Chemistry and Biology. 8, 3, p. 277-287 11 p.

Research output: Contribution to journalArticle

The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions

Webb, P., Nguyen, P., Valentine, C., Lopez, G. N., Kwok, G. R., McInerney, E., Katzenellenbogen, B. S., Enmark, E., Gustafsson, J. Å., Nilsson, S. & Kushner, P. J., Jan 1 1999, In : Molecular Endocrinology. 13, 10, p. 1672-1685 14 p.

Research output: Contribution to journalArticle

The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells

Stender, J. D., Stossi, F., Funk, C. C., Charn, T. H., Barnett, D. H. & Katzenellenbogen, B. S., Oct 1 2011, In : Molecular Endocrinology. 25, 10, p. 1699-1709 11 p.

Research output: Contribution to journalArticle

Therapeutic Targeting in the Estrogen Receptor Hormonal Pathway

Katzenellenbogen, B. S. & Frasor, J., Feb 2004, In : Seminars in Oncology. 31, 1 SUPPL. 3, p. 28-38 11 p.

Research output: Contribution to journalArticle

The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells

Alyea, R. A., Laurence, S. E., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A. & Watson, C. S., Aug 1 2008, In : Journal of Neurochemistry. 106, 4, p. 1525-1533 9 p.

Research output: Contribution to journalArticle

The stability of the uterine estrogen receptor when complexed with estrogens or antiestrogens

Pavlik, E. J. & Katzenellenbogen, B. S., 1980, In : Molecular Pharmacology. 18, 3, p. 406-412 7 p.

Research output: Contribution to journalArticle

The tissue-specific effects of different 17β-estradiol doses reveal the key sensitizing role of AF1 domain in ERα activity

Fontaine, C., Buscato, M., Vinel, A., Giton, F., Raymond-Letron, I., Kim, S. H., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Gourdy, P., Milon, A., Flouriot, G., Ohlsson, C., Lenfant, F. & Arnal, J. F., Apr 5 2020, In : Molecular and Cellular Endocrinology. 505, 110741.

Research output: Contribution to journalArticle

The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valéra, M. C., Gompel, A., Gerard, C., Péqueux, C., Mestdagt, M., Raymond-Letron, I., Knauf, C. & 9 others, Ferriere, F., Valet, P., Gourdy, P., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Lenfant, F., Greene, G. L., Foidart, J. M. & Arnal, J. F., Oct 1 2014, In : EMBO Molecular Medicine. 6, 10, p. 1328-1346 19 p.

Research output: Contribution to journalArticle

Thyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells

Zhao, X., Lorenc, H., Stephenson, H., Wang, Y. J., Witherspoon, D., Katzenellenbogen, B., Pfaff, D. & Vasudevan, N., Mar 29 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4890-4895 6 p.

Research output: Contribution to journalArticle

Transcription activation by the human estrogen receptor subtype β (ERβ) studied with ERβ and ERα receptor chimeras

Mcinerney, E. M., Weis, K. E., Sun, J., Mosselman, S. & Katzenellenbogen, B. S., Jan 1 1998, In : Endocrinology. 139, 11, p. 4513-4522 10 p.

Research output: Contribution to journalArticle

Transcriptional profiling of estrogen-regulated gene expression via estrogen receptor (ER) α or ERβ in human osteosarcoma cells: Distinct and common target genes for these receptors

Stossi, F., Barnett, D. H., Frasor, J., Komm, B., Lyttle, C. R. & Katzenellenbogen, B. S., Jul 1 2004, In : Endocrinology. 145, 7, p. 3473-3486 14 p.

Research output: Contribution to journalArticle

Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-α and estrogen receptor-β

Montano, M. M., Jaiswal, A. K. & Katzenellenbogen, B. S., Sep 25 1998, In : Journal of Biological Chemistry. 273, 39, p. 25443-25449 7 p.

Research output: Contribution to journalArticle