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Article
2020

Gene expression amplification by nuclear speckle association

Kim, J., Venkata, N. C., Gonzalez, G. A. H., Khanna, N. & Belmont, A. S., Jan 6 2020, In : Journal of Cell Biology. 219, 1

Research output: Contribution to journalArticle

Open Access
2019

Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition

Kim, J., Han, K. Y., Khanna, N., Ha, T. & Belmont, A. S., Apr 1 2019, In : Journal of cell science. 132, 8, 226563.

Research output: Contribution to journalArticle

Open Access
2018

CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci

Tasan, I., Sustackova, G., Zhang, L., Kim, J., Sivaguru, M., HamediRad, M., Wang, Y., Genova, J., Ma, J., Belmont, A. S. & Zhao, H., Jan 1 2018, In : Nucleic acids research. 46, 17, e100.

Research output: Contribution to journalArticle

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

Chen, Y., Zhang, Y., Wang, Y., Zhang, L., Brinkman, E. K., Adam, S. A., Goldman, R., Van Steensel, B., Ma, J. & Belmont, A. S., Nov 1 2018, In : Journal of Cell Biology. 217, 11, p. 4025-4048 24 p.

Research output: Contribution to journalArticle

Stable and reproducible transgene expression independent of proliferative or differentiated state using BAC TG-EMBED

Chaturvedi, P., Zhao, B., Zimmerman, D. L. & Belmont, A. S., Aug 1 2018, In : Gene therapy. 25, 5, p. 376-391 16 p.

Research output: Contribution to journalArticle

2016

Cytology of DNA Replication Reveals Dynamic Plasticity of Large-Scale Chromatin Fibers

Deng, X., Zhironkina, O. A., Cherepanynets, V. D., Strelkova, O. S., Kireev, I. I. & Belmont, A. S., Sep 26 2016, In : Current Biology. 26, 18, p. 2527-2534 8 p.

Research output: Contribution to journalArticle

Labeling proteins inside living cells using external fluorophores for microscopy

Teng, K. W., Ishitsuka, Y., Ren, P., Youn, Y., Deng, X., Ge, P., Belmont, A. S. & Selvin, P. R., Dec 9 2016, In : eLife. 5, DECEMBER2016, e20378.

Research output: Contribution to journalArticle

Transcription upregulation via force-induced direct stretching of chromatin

Tajik, A., Zhang, Y., Wei, F., Sun, J., Jia, Q., Zhou, W., Singh, R., Khanna, N., Belmont, A. S. & Wang, N., Dec 1 2016, In : Nature Materials. 15, 12, p. 1287-1296 10 p.

Research output: Contribution to journalArticle

2015

Overcoming steric hindrances during replication of peripheral heterochromatin

Zhironkina, O. A., Kurchashova, S. Y., Brattseva, A. L., Cherepaninets, V. D., Strelkova, O. S., Belmont, A. S. & Kireev, I. I., Mar 1 2015, In : Cell and Tissue Biology. 9, 2, p. 110-118 9 p.

Research output: Contribution to journalArticle

2014

HSP70 transgene directed motion to nuclear speckles facilitates heat shock activation

Khanna, N., Hu, Y. & Belmont, A. S., May 19 2014, In : Current Biology. 24, 10, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

Resolution of spatial constraints during replication of peripheral chromatin

Zhironkina, O. A., Kurchashova, S. Y., Bratseva, A. L., Cherepanynets, V. D., Strelkova, O. S., Belmont, A. S. & Kireev, I. I., Jan 1 2014, In : Tsitologiia. 56, 12, p. 899-906 8 p.

Research output: Contribution to journalArticle

2013

β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications

Bian, Q., Khanna, N., Alvikas, J. & Belmont, A. S., Dec 9 2013, In : Journal of Cell Biology. 203, 5, p. 767-783 17 p.

Research output: Contribution to journalArticle

2011

Live-cell chromosome dynamics and outcome of X chromosome pairing events during ES cell differentiation

Masui, O., Bonnet, I., Le Baccon, P., Brito, I., Pollex, T., Murphy, N., Hupé, P., Barillot, E., Belmont, A. S. & Heard, E., Apr 29 2011, In : Cell. 145, 3, p. 447-458 12 p.

Research output: Contribution to journalArticle

2010

BAC TG-EMBED: One-step method for high-level, copy-number-dependent, position-independent transgene expression

Bian, Q. & Belmont, A. S., Apr 10 2010, In : Nucleic acids research. 38, 11, p. e127-e127 gkq178.

Research output: Contribution to journalArticle

Dynamic plasticity of large-scale chromatin structure revealed by self-assembly of engineered chromosome regions

Sinclair, P., Bian, Q., Plutz, M., Heard, E. & Belmont, A. S., Sep 6 2010, In : Journal of Cell Biology. 190, 5, p. 761-776 16 p.

Research output: Contribution to journalArticle

Estrogen fueled, nuclear kiss: Did it move for you?

Belmont, A. S., Jan 1 2010, In : Nucleus. 1, 5, 13051.

Research output: Contribution to journalArticle

Hsp70 gene association with nuclear speckles is Hsp70 promoter specific

Hu, Y., Plutz, M. & Belmont, A. S., Nov 15 2010, In : Journal of Cell Biology. 191, 4, p. 711-719 9 p.

Research output: Contribution to journalArticle

Insights into interphase large-scale chromatin structure from analysis of engineered chromosome regions

Belmont, A. S., Hu, Y., Sinclair, P. B., Wu, W., Bian, Q. & Kireev, I., Dec 1 2010, In : Cold Spring Harbor symposia on quantitative biology. 75, p. 453-460 8 p.

Research output: Contribution to journalArticle

2009

Complexity in transcription control at the activation domain-Mediator interface

Balamotis, M. A., Pennella, M. A., Stevens, J. L., Wasylyk, B., Belmont, A. S. & Berk, A. J., May 5 2009, In : Science Signaling. 2, 69, p. ra20

Research output: Contribution to journalArticle

Large-scale chromatin structure of inducible genes: Transcription on a condensed, linear template

Hu, Y., Kireev, I., Plutz, M., Ashourian, N. & Belmont, A. S., Apr 6 2009, In : Journal of Cell Biology. 185, 1, p. 87-100 14 p.

Research output: Contribution to journalArticle

Mitotic chromosome structure: Reproducibility of folding and symmetry between sister chromatids

Strukov, Y. G. & Belmont, A. S., Feb 18 2009, In : Biophysical journal. 96, 4, p. 1617-1628 12 p.

Research output: Contribution to journalArticle

2008

Development of mammalian cells lines with lac operator-tagged chromosomes

Strukov, Y. G. & Belmont, A. S., Jan 1 2008, In : Cold Spring Harbor Protocols. 3, 1

Research output: Contribution to journalArticle

Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila

Deng, H., Bao, X., Cai, W., Blacketer, M. J., Belmont, A. S., Girton, J., Johansen, J. & Johansen, K. M., Feb 2008, In : Development. 135, 4, p. 699-705 7 p.

Research output: Contribution to journalArticle

In vivo immunogold labeling confirms large-scale chromatin folding motifs

Kireev, I., Lakonishok, M., Liu, W., Joshi, V. N., Powell, R. & Belmont, A. S., Apr 1 2008, In : Nature Methods. 5, 4, p. 311-313 3 p.

Research output: Contribution to journalArticle

The facultative heterochromatin of the inactive X chromosome has a distinctive condensed ultrastructure

Rego, A., Sinclair, P. B., Tao, W., Kireev, I. & Belmont, A. S., Apr 1 2008, In : Journal of cell science. 121, 7, p. 1119-1127 9 p.

Research output: Contribution to journalArticle

2007

High-pressure treatment of polytene chromosomes improves structural resolution

Novikov, D. V., Kireev, I. & Belmont, A. S., Jun 1 2007, In : Nature Methods. 4, 6, p. 483-485 3 p.

Research output: Contribution to journalArticle

2006

Long-Range Directional Movement of an Interphase Chromosome Site

Chuang, C. H., Carpenter, A. E., Fuchsova, B., Johnson, T., de Lanerolle, P. & Belmont, A. S., Apr 18 2006, In : Current Biology. 16, 8, p. 825-831 7 p.

Research output: Contribution to journalArticle

Truncated HP1 lacking a functional chromodomain induces heterochromatinization upon in vivo targeting

Brink, M. C., Van Der Velden, Y., De Leeuw, W., Mateos-Langerak, J., Belmont, A. S., Van Driel, R. & Verschure, P. J., Jan 1 2006, In : Histochemistry and Cell Biology. 125, 1-2, p. 53-61 9 p.

Research output: Contribution to journalArticle

2005

Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope

Levi, V., Ruan, Q. Q., Plutz, M., Belmont, A. S. & Gratton, E., Dec 2005, In : Biophysical journal. 89, 6, p. 4275-4285 11 p.

Research output: Contribution to journalArticle

Common effects of acidic activators on large-scale chromatin structure and transcription

Carpenter, A. E., Memedula, S., Plutz, M. J. & Belmont, A. S., Feb 1 2005, In : Molecular and cellular biology. 25, 3, p. 958-968 11 p.

Research output: Contribution to journalArticle

In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation

Verschure, P. J., Van Der Kraan, I., De Leeuw, W., Van Der Vlag, J., Carpenter, A. E., Belmont, A. S. & Van Driel, R., Jun 2005, In : Molecular and cellular biology. 25, 11, p. 4552-4564 13 p.

Research output: Contribution to journalArticle

2004

Automated Microscopy Identifies Estrogen Receptor Subdomains with Large-Scale Chromatin Structure Unfolding Activity

Carpenter, A. E., Ashouri, A. & Belmont, A. S., Apr 2004, In : Cytometry Part A. 58, 2, p. 157-166 10 p.

Research output: Contribution to journalArticle

Differential large-scale chromatin compaction and intranuclear positioning of transcribed versus nontranscribed transgene arrays containing β-globin regulatory sequences

Dietzel, S., Zolghadr, K., Hepperger, C. & Belmont, A. S., Sep 1 2004, In : Journal of cell science. 117, 19, p. 4603-4614 12 p.

Research output: Contribution to journalArticle

Upstream binding factor association induces large-scale chromatin decondensation

Chen, D., Belmont, A. S. & Huang, S., Oct 19 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 42, p. 15106-15111 6 p.

Research output: Contribution to journalArticle

Visualization of early chromosome condensation: A hierarchical folding, axial glue model of chromosome structure

Kireeva, N., Lakonishok, M., Kireev, I., Hirano, T. & Belmont, A. S., Sep 13 2004, In : Journal of Cell Biology. 166, 6, p. 775-785 11 p.

Research output: Contribution to journalArticle

2003

Direct Visualization of Transcription Factor-Induced Chromatin Remodeling and Cofactor Recruitment In Vivo

Carpenter, A. E. & Belmont, A. S., Jan 1 2003, In : Methods in enzymology. 375, p. 366-381 16 p.

Research output: Contribution to journalArticle

Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes

Strukov, Y. G., Wang, Y. & Belmont, A. S., Jul 7 2003, In : Journal of Cell Biology. 162, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16

Memedula, S. & Belmont, A. S., Feb 2003, In : Current Biology. 13, 3, p. 241-246 6 p.

Research output: Contribution to journalArticle

2002

Alteration of large-scale chromatin structure by estrogen receptor

Nye, A. C., Rajendran, R. R., Stenoien, D. L., Mancini, M. A., Katzenellenbogen, B. S. & Belmont, A. S., May 9 2002, In : Molecular and cellular biology. 22, 10, p. 3437-3449 13 p.

Research output: Contribution to journalArticle

The dynamics of homologous chromosome pairing during male Drosophila meiosis

Vazquez, J., Belmont, A. S. & Sedat, J. W., Sep 3 2002, In : Current Biology. 12, 17, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

2001

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

Ye, Q., Hu, Y. F., Zhong, H., Nye, A. C., Belmont, A. S. & Li, R., Dec 10 2001, In : Journal of Cell Biology. 155, 6, p. 911-921 11 p.

Research output: Contribution to journalArticle

Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator

Tumbar, T. & Belmont, A. S., Feb 15 2001, In : Nature Cell Biology. 3, 2, p. 134-139 6 p.

Research output: Contribution to journalArticle

Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor α-coactivator complexes in living cells

Stenoien, D. L., Nye, A. C., Mancini, M. G., Patel, K., Dutertre, M., O'Malley, B. W., Smith, C. L., Belmont, A. S. & Mancini, M. A., Jul 4 2001, In : Molecular and cellular biology. 21, 13, p. 4404-4412 9 p.

Research output: Contribution to journalArticle

Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus

Vazquez, J., Belmont, A. S. & Sedat, J. W., Aug 21 2001, In : Current Biology. 11, 16, p. 1227-1239 13 p.

Research output: Contribution to journalArticle

Reproducible but dynamic positioning of DNA in chromosomes during mitosis

Dietzel, S. & Belmont, A. S., Aug 21 2001, In : Nature Cell Biology. 3, 8, p. 767-770 4 p.

Research output: Contribution to journalArticle

2000

Visualization of gene activity in living cells

Tsukamoto, T., Hashiguchi, N., Janicki, S. M., Tumbar, T., Belmont, A. S. & Spector, D. L., Dec 18 2000, In : Nature Cell Biology. 2, 12, p. 871-878 8 p.

Research output: Contribution to journalArticle

1999

Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain

Tumbar, T., Sudlow, G. & Belmont, A. S., Jun 28 1999, In : Journal of Cell Biology. 145, 7, p. 1341-1354 14 p.

Research output: Contribution to journalArticle

Visualization of large-scale chromatin structure and dynamics using the lac operator/lac repressor reporter system

Belmont, A. S., Li, G., Sudlow, G. & Robinett, C., Dec 1 1999, In : Methods in Cell Biology. 58, p. 203-222 20 p.

Research output: Contribution to journalArticle

1998

In vivo visualization of chromosomes using lac operator-repressor binding

Belmont, A. S. & Straight, A. F., Mar 1998, In : Trends in Cell Biology. 8, 3, p. 121-124 4 p.

Research output: Contribution to journalArticle