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2010

Spatiotemporal organization, regulation, and functions of tractions during neutrophil chemotaxis

Shin, M. E., He, Y., Li, D., Na, S., Chowdhury, F., Poh, Y. C., Collin, O., Su, P., De Lanerolle, P., Schwartz, M. A., Wang, N. & Wang, F., Oct 28 2010, In : Blood. 116, 17, p. 3297-3310 14 p.

Research output: Contribution to journalArticle

Myosin Type II
Traction
Chemotaxis
Neutrophils
Nonmuscle Myosin Type IIA

The G-protein-coupled receptor, GPR84, is important for eye development in Xenopus laevis

Perry, K. J., Johnson, V. R., Malloch, E. L., Fukui, L., Wever, J., Thomas, A. G., Hamilton, P. W. & Henry, J. J., Nov 1 2010, In : Developmental Dynamics. 239, 11, p. 3024-3037 14 p.

Research output: Contribution to journalArticle

Xenopus laevis
G-Protein-Coupled Receptors
Lenses
Retina
Cornea

The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation

Tripathi, V., Ellis, J. D., Shen, Z., Song, D. Y., Pan, Q., Watt, A. T., Freier, S. M., Bennett, C. F., Sharma, A., Bubulya, P. A., Blencowe, B. J., Prasanth, S. G. & Kannanganattu, P. K., Sep 1 2010, In : Molecular cell. 39, 6, p. 925-938 14 p.

Research output: Contribution to journalArticle

Untranslated RNA
Alternative Splicing
Serine
Arginine
Phosphorylation

The slipper snail, Crepidula: An emerging lophotrochozoan model system

Henry, J. J., Collin, R. & Perry, K. J., Jun 1 2010, In : Biological Bulletin. 218, 3, p. 211-229 19 p.

Research output: Contribution to journalArticle

Snails
snails
Developmental Biology
Mollusca
Expressed Sequence Tags

Topography and refractometry of nanostructures using spatial light interference microscopy

Wang, Z., Chun, I. S., Li, X., Ong, Z. Y., Pop, E., Millet, L., Gillette, M. & Popescu, G., Jan 15 2010, In : Optics Letters. 35, 2, p. 208-210 3 p.

Research output: Contribution to journalArticle

topography
microscopy
interference
neurons
decoupling

β-catenin and early development in the Gastropod, Crepidula fornicata

Henry, J. J., Perry, K. J. & Martindale, M. Q., Nov 1 2010, In : Integrative and Comparative Biology. 50, 5, p. 707-719 13 p.

Research output: Contribution to journalArticle

early development
Gastropoda
embryo (animal)
cells
hindgut
2009

A MicroRNA Imparts Robustness against Environmental Fluctuation during Development

Li, X., Cassidy, J. J., Reinke, C. A., Fischboeck, S. & Carthew, R. W., Apr 17 2009, In : Cell. 137, 2, p. 273-282 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Drosophila
Buffers
Mammals
Genes
Lipolysis
Sirolimus
Adipocytes
Insulin
Amino Acids

Comparative toxicity of mycotoxins to navel orangeworm (Amyelois transitella) and corn earworm (Helicoverpa zea)

Niu, G., Siegel, J., Schuler, M. A. & Berenbaum, M. R., Aug 14 2009, In : Journal of Chemical Ecology. 35, 8, p. 951-957 7 p.

Research output: Contribution to journalArticle

Amyelois transitella
Aflatoxins
Helicoverpa zea
Mycotoxins
mycotoxins

Complexity in transcription control at the activation domain-Mediator interface

Balamotis, M. A., Pennella, M. A., Stevens, J. L., Wasylyk, B., Belmont, A. S. & Berk, A. J., May 5 2009, In : Science Signaling. 2, 69, p. ra20

Research output: Contribution to journalArticle

Ternary Complex Factors
Early Growth Response Protein 1
Transcription
Fibroblasts
Embryonic Stem Cells

Cytochrome P450 monooxygenases as reporters for circadian-regulated pathways

Pan, Y., Michael, T. P., Hudson, M., Kay, S. A., Chory, J. & Schuler, M. A., Jun 1 2009, In : Plant physiology. 150, 2, p. 858-878 21 p.

Research output: Contribution to journalArticle

Mixed Function Oxygenases
Seedlings
cytochrome P-450
Cytochrome P-450 Enzyme System
promoter regions
Pan troglodytes
Transcription Factors
Gene Expression
Brain
Genes

Domains of heterochromatin protein 1 required for Drosophila melanogaster heterochromatin spreading

Hines, K. A., Cryderman, D. E., Flannery, K. M., Hongbo, Y., Vitalini, M. W., Hazelrigg, T., Mizzen, C. A. & Wallrath, L. L., Aug 1 2009, In : Genetics. 182, 4, p. 967-977 11 p.

Research output: Contribution to journalArticle

Heterochromatin
Drosophila melanogaster
Reporter Genes
Protein Multimerization
Genome

Ecological significance of induction of broad-substrate cytochrome p450s by natural and synthetic inducers in Helicoverpa Zea

Wen, Z., Zeng, R. S., Niu, G., Berenbaum, M. R. & Schuler, M. A., Feb 1 2009, In : Journal of Chemical Ecology. 35, 2, p. 183-189 7 p.

Research output: Contribution to journalArticle

Helicoverpa zea
Phytochemicals
Cytochromes
cytochromes
toxin

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization

Simons, M., Gault, W. J., Gotthardt, D., Rohatgi, R., Klein, T. J., Shao, Y., Lee, H. J., Wu, A. L., Fang, Y., Satlin, L. M., Dow, J. T., Chen, J., Zheng, J., Boutros, M. & Mlodzik, M., Feb 24 2009, In : Nature Cell Biology. 11, 3, p. 286-294 9 p.

Research output: Contribution to journalArticle

Cues
Phospholipids
Cell Membrane
Basic Amino Acids
Cell Polarity

Enhanced toxicity and induction of cytochrome P450s suggest a cost of "eavesdropping" in a multitrophic interaction

Zeng, R. S., Wen, Z., Niu, G., Schuler, M. A. & Berenbaum, M. R., May 1 2009, In : Journal of Chemical Ecology. 35, 5, p. 526-532 7 p.

Research output: Contribution to journalArticle

Mixed Function Oxygenases
cytochrome P-450
Cytochrome P-450 Enzyme System
cytochrome
Toxicity

FIONA on Caenorhabditis elegans

Kural, C., Nonet, M. L. & Selvin, P. R., Jun 9 2009, In : Biochemistry. 48, 22, p. 4663-4665 3 p.

Research output: Contribution to journalArticle

Optical Imaging
Caenorhabditis elegans
Fluorescence
Imaging techniques
Fluorescent Dyes

Fragile X Mental Retardation Protein FMRP binds mRNAs in the nucleus

Kim, M., Bellini, M. & Ceman, S., Jan 1 2009, In : Molecular and cellular biology. 29, 1, p. 214-228 15 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Messenger RNA
Simian virus 40
Cell Nucleus Active Transport
RNA-Binding Proteins

Gene expression profiles of lens regeneration and development in Xenopus laevis

Malloch, E. L., Perry, K. J., Fukui, L., Johnson, V. R., Wever, J., Beck, C. W., King, M. W. & Henry, J. J., Sep 21 2009, In : Developmental Dynamics. 238, 9, p. 2340-2356 17 p.

Research output: Contribution to journalArticle

Xenopus laevis
Transcriptome
Lenses
Regeneration
Genes

Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers

Iizuka, M., Takahashi, Y., Mizzen, C. A., Cook, R. G., Fujita, M., Allis, C. D., Frierson, H. F., Fukusato, T. & Smith, M. M., May 1 2009, In : Gene. 436, 1-2, p. 108-114 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
DNA Replication
Chromatin
Neoplasms
Replication Origin

Large-scale chromatin structure of inducible genes: Transcription on a condensed, linear template

Hu, Y., Kireev, I., Plutz, M., Ashourian, N. & Belmont, A. S., Apr 6 2009, In : Journal of Cell Biology. 185, 1, p. 87-100 14 p.

Research output: Contribution to journalArticle

Chromatin
Interphase
Transgenes
Genes
Chromosome Structures

Lineage-specific biology revealed by a finished genome assembly of the mouse

Church, D. M., Goodstadt, L., Hillier, L. W., Zody, M. C., Goldstein, S., She, X., Bult, C. J., Agarwala, R., Cherry, J. L., DiCuccio, M., Hlavina, W., Kapustin, Y., Meric, P., Maglott, D., Birtle, Z., Marques, A. C., Graves, T., Zhou, S., Teague, B., Potamousis, K. & 155 others, Churas, C., Place, M., Herschleb, J., Runnheim, R., Forrest, D., Amos-Landgraf, J., Schwartz, D. C., Cheng, Z., Lindblad-Toh, K., Eichler, E. E., Ponting, C. P., Muzny, D. M., Dugan-Rocha, S., Ding, Y., Scherer, S. E., Buhay, C. J., Cree, A., Hernandez, J., Holder, M., Hume, J., Jackson, L. R., Kovar, C., Lee, S. L., Lewis, L. R., Metzker, M. L., Narareth, L. V., Sabo, A., Sodergren, E., Gibbs, R. A., FitzGerald, M., Cook, A., Jaffe, D. B., Garber, M., Zimmer, A. R., Pirun, M., Russell, L., Sharpe, T., Chaturvedi, M. K. K., Wilkinson, J., LaButti, K., Yang, X., Bessette, D., Allen, N. R., Nguyen, C., Nguyen, T., Dunbar, C., Lubonja, R., Matthews, C., Liu, X., Benamara, M., Negash, T., Lokyitsang, T., Decktor, K., Piqani, B., Munson, G., Tenzin, P., Stone, S., Macdonald, P., Arachchi, H., Abouelleil, A., Lui, A., Priest, M., Gearin, G., Brown, A., Aftuck, L., Shea, T., Sykes, S., Berlin, A., Chu, J., Dooley, K., Hagopian, D., Hall, J., Hafez, N., Smith, C. L., Olandt, P., Miller, K., Ventkataraman, V., Rachupka, A., Dorris, L., Ayotte, L., Mabbitt, R., Erickson, J., Horn, A., An, P., Naylor, J. W., Settipalli, S., Lander, E. S., Wilson, R. K., Graves, T. A., Fulton, R. S., Rock, S. M., Chinwalla, A. T., Bernard, K., Courtney, L. P., Fronick, C., Fulton, L. L., O'Laughlin, M., Kremitzki, C. L., Minx, P. J., Nelson, J. O., Schatzkamer, K. L., Strong, C., Wollam, A. M., Weinstock, G. M., Yang, S. P., Rogers, J., Grafham, D., Humphray, S., Nicholson, C., Bird, C., Brown, A. J., Burton, J., Clee, C., Hunt, A., Jones, M. C., Lloyd, C., Matthews, L., Mclaren, K., Mclaren, S., McLay, K., Palmer, S. A., Plumb, R., Shownkeen, R., Sims, S., Quail, M. A., Whitehead, S. L., Willey, D. L., Deschamps, S., Kenton, S., Song, L., Do, T., Roe, B., Bouffard, G. G., Blakesley, R. W., Green, E. D., Kucherlapati, R., Grills, G., Li, L., Montgomery, K. T., Kramer, M., Speigel, L., McCombie, W. R., Lucas, S., Terry, A., Gordon, L., Stubbs, L., Denny, P., Brown, S. D. M., Mallon, A. M., Campbell, R. D., Botherby, M. R. M., Jackson, I. J., Rubenfield, M. J., Rogosin, A. M. & Smith, D. R., May 1 2009, In : PLoS biology. 7, 5, e1000112.

Research output: Contribution to journalArticle

genome assembly
Genes
Genome
Biological Sciences
mice

Mitotic chromosome structure: Reproducibility of folding and symmetry between sister chromatids

Strukov, Y. G. & Belmont, A. S., Feb 18 2009, In : Biophysical journal. 96, 4, p. 1617-1628 12 p.

Research output: Contribution to journalArticle

Chromosome Structures
Chromatids
Chromosomes
Metaphase
Chromatin

mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms

Ge, Y., Wu, A. L., Warnes, C., Liu, J., Zhang, C., Kawasome, H., Terada, N., Boppart, M. D., Schoenherr, C. J. & Chen, J., Dec 1 2009, In : American Journal of Physiology - Cell Physiology. 297, 6

Research output: Contribution to journalArticle

Sirolimus
Regeneration
Skeletal Muscle
Phosphotransferases
Muscles

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

Zhou, J., Su, P., Wang, L., Chen, J., Zimmermann, M., Genbacev, O., Afonja, O., Horne, M. C., Tanaka, T., Duan, E., Fisher, S. J., Liao, J., Chen, J. & Wang, F., May 12 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 19, p. 7840-7845 6 p.

Research output: Contribution to journalArticle

Endoderm
Mesoderm
Sirolimus
Developmental Genes
Protein-Serine-Threonine Kinases

Myosin VI Dimerization Triggers an Unfolding of a Three-Helix Bundle in Order to Extend Its Reach

Mukherjea, M., Llinas, P., Kim, H. J., Travaglia, M., Safer, D., Ménétrey, J., Franzini-Armstrong, C., Selvin, P. R., Houdusse, A. & Sweeney, H. L., Aug 14 2009, In : Molecular cell. 35, 3, p. 305-315 11 p.

Research output: Contribution to journalArticle

Dimerization
Actins
Myosins
Reference Values
Fluorescence

Myosin VI undergoes a 180° power stroke implying an uncoupling of the front lever arm

Reifenberger, J. G., Toprak, E., Kim, H. J., Safer, D., Sweeney, H. L. & Selvin, P. R., Dec 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 43, p. 18255-18260 6 p.

Research output: Contribution to journalArticle

Stroke
Head
Light
Rhodamines
Solar System

Orc1 controls centriole and centrosome copy number in human cells

Hemerly, A. S., Prasanth, S. G., Siddiqui, K. & Stillman, B., Feb 6 2009, In : Science. 323, 5915, p. 789-793 5 p.

Research output: Contribution to journalArticle

Centrioles
Centrosome
DNA Replication
Origin Recognition Complex
Cyclin A

Phosphorylation of FMRP inhibits association with Dicer

Cheever, A. & Ceman, S., Mar 1 2009, In : RNA. 15, 3, p. 362-366 5 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Phosphorylation
MicroRNAs
Phospho-Specific Antibodies
Fragile X Syndrome

Quercetin-metabolizing CYP6AS enzymes of the pollinator Apis mellifera (Hymenoptera: Apidae)

Mao, W., Rupasinghe, S. G., Johnson, R. M., Zangerl, A. R., Schuler, M. A. & Berenbaum, M. R., Dec 1 2009, In : Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 154, 4, p. 427-434 8 p.

Research output: Contribution to journalArticle

Hymenoptera
Honey
Bees
Quercetin
Genes

Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin ignaling through serine 727 phosphorylation

Kim, J. H., Yoon, M. S. & Chen, J., Dec 18 2009, In : Journal of Biological Chemistry. 284, 51, p. 35425-35432 8 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Phosphorylation
Serine
Insulin
Amino Acids

Silencing by small RNAs is linked to endosomal trafficking

Lee, Y. S., Pressman, S., Andress, A. P., Kim, K., White, J. L., Cassidy, J. J., Li, X., Lubell, K., Lim, D. H., Cho, I. S., Nakahara, K., Preall, J. B., Bellare, P., Sontheimer, E. J. & Carthew, R. W., Aug 17 2009, In : Nature Cell Biology. 11, 9, p. 1150-1156 7 p.

Research output: Contribution to journalArticle

RNA-Induced Silencing Complex
Multivesicular Bodies
RNA Interference
RNA
MicroRNAs

Temporally restricted role of retinal PACAP: Integration of the phase-advancing light signal to the SCN

Beaulé, C., Mitchell, J. W., Lindberg, P. T., Damadzic, R., Eiden, L. E. & Gillette, M. U., Apr 1 2009, In : Journal of biological rhythms. 24, 2, p. 126-134 9 p.

Research output: Contribution to journalArticle

Suprachiasmatic Nucleus
Adenylyl Cyclases
Light
Peptides
Circadian Clocks

Textural guidance cues for controlling process outgrowth of mammalian neurons

Hanson, J. N., Motala, M. J., Heien, M. L., Gillette, M., Sweedler, J. & Nuzzo, R. G., Jan 1 2009, In : Lab on a chip. 9, 1, p. 122-131 10 p.

Research output: Contribution to journalArticle

Neurons
Cues
Growth
Aplysia
Substrates

The conserved Est1 protein stimulates telomerase DNA extension activity

DeZwaan, D. C. & Freeman, B. C., Oct 13 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 41, p. 17337-17342 6 p.

Research output: Contribution to journalArticle

Telomerase
DNA
Proteins
Holoenzymes
Saccharomycetales

The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states

DeZwaan, D. C., Toogun, O. A., Echtenkamp, F. J. & Freeman, B. C., Jul 1 2009, In : Nature Structural and Molecular Biology. 16, 7, p. 711-716 6 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Telomere
Telomerase
Yeasts
DNA

Why kinesin is so processive

Toprak, E., Yildiz, A., Hoffman, M. T., Rosenfeld, S. S. & Selvin, P. R., Aug 4 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 12717-12722 6 p.

Research output: Contribution to journalArticle

Kinesin
Microtubules
Adenosine Triphosphate
Head
Fluorescence
2008

Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers

Hao, Y. K., Charras, G. T., Mitchison, T. J. & Brieher, W. M., Jul 28 2008, In : Journal of Cell Biology. 182, 2, p. 341-353 13 p.

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Actins
Cytochalasin D
Actin Cytoskeleton
Pharmaceutical Preparations

Aflatoxin B1 detoxification by CYP321A1 in Helicoverpa zea

Niu, G., Wen, Z., Rupasinghe, S. G., Ren, S. Z., Berenbaum, M. R. & Schuler, M. A., Sep 1 2008, In : Archives of Insect Biochemistry and Physiology. 69, 1, p. 32-45 14 p.

Research output: Contribution to journalArticle

Detoxification
Aflatoxin B1
Helicoverpa zea
aflatoxin B1
midgut

A quantitative analysis of contractility in active cytoskeletal protein networks

Bendix, P. M., Koenderink, G. H., Cuvelier, D., Dogic, Z., Koeleman, B. N., Brieher, W. M., Field, C. M., Mahadevan, L. & Weitz, D. A., Apr 15 2008, In : Biophysical journal. 94, 8, p. 3126-3136 11 p.

Research output: Contribution to journalArticle

Myosin Type II
Cytoskeletal Proteins
Myosins
Actins
Actinin

Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle

Pesavento, J. J., Yang, H., Kelleher, N. L. & Mizzen, C. A., Jan 1 2008, In : Molecular and cellular biology. 28, 1, p. 468-486 19 p.

Research output: Contribution to journalArticle

Histones
Methylation
Lysine
Cell Cycle
Acetylation

Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry

Pesavento, J. J., Bullock, C. R., LeDuc, R. D., Mizzen, C. A. & Kelleher, N. L., May 30 2008, In : Journal of Biological Chemistry. 283, 22, p. 14927-14937 11 p.

Research output: Contribution to journalArticle

Liquid chromatography
Liquid Chromatography
Acetylation
Histones
Methylation

Comparative molecular modeling of Anopheles gambiae CYP6Z1, a mosquito P450 capable of metabolizing DDT

Chiu, T. L., Wen, Z., Rupasinghe, S. G. & Schuler, M. A., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 8855-8860 6 p.

Research output: Contribution to journalArticle

Anopheles gambiae
DDT
Culicidae
Catalytic Domain
Insecticide Resistance

Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1

Kühnel, K., Ke, N., Cryle, M. J., Sligar, S. G., Schuler, M. A. & Schlichting, I., Jun 24 2008, In : Biochemistry. 47, 25, p. 6552-6559 8 p.

Research output: Contribution to journalArticle

Tretinoin
Cytochrome P-450 Enzyme System
Crystal structure
Substrates
Norisoprenoids

Dynamic stabilization of actin filaments

Hao, Y. K., Brieher, W. M. & Mitchison, T. J., Oct 28 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16531-16536 6 p.

Research output: Contribution to journalArticle

Open Access
Actin Cytoskeleton
Actin Depolymerizing Factors
Actins
Polymerization
Electron Microscopy

Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila

Deng, H., Bao, X., Cai, W., Blacketer, M. J., Belmont, A. S., Girton, J., Johansen, J. & Johansen, K. M., Feb 1 2008, In : Development. 135, 4, p. 699-705 7 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Histones
Drosophila
Chromatin
Phosphorylation

Expression of fragile X mental retardation protein within the vocal control system of developing and adult male zebra finches

Winograd, C., Clayton, D. & Ceman, S., Nov 11 2008, In : Neuroscience. 157, 1, p. 132-142 11 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Finches
Equidae
Music
Learning

Extent of Voltage Sensor Movement during Gating of Shaker K+ Channels

Posson, D. J. & Selvin, P. R., Jul 10 2008, In : Neuron. 59, 1, p. 98-109 12 p.

Research output: Contribution to journalArticle

Energy Transfer
Luminescence
Structural Models
Research

Forkhead box protein O1 negatively regulates skeletal myocyte differentiation through degradation of mammalian target of rapamycin pathway components

Wu, A. L., Kim, J. H., Zhang, C., Unterman, T. G. & Chen, J., Mar 1 2008, In : Endocrinology. 149, 3, p. 1407-1414 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle Fibers
Sirolimus
Insulin-Like Growth Factor II
Muscle Development
Phosphatidylinositol 3-Kinase

Identification and characterization of topoisomerase II inhibitory peptides from soy protein hydrolysates

Wang, W., Rupasinghe, S. G., Schuler, M. A. & De Mejia, E. G., Aug 13 2008, In : Journal of Agricultural and Food Chemistry. 56, 15, p. 6267-6277 11 p.

Research output: Contribution to journalArticle

Protein Hydrolysates
DNA topoisomerase (ATP-hydrolysing)
Type II DNA Topoisomerase
Soybean Proteins
peptides