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"ORCanization" On heterochromatin linking DNA replication initiation to chromatin organization

Chakraborty, A., Shen, Z. & Prasanth, S. G., Jun 2011, In : Epigenetics. 6, 6, p. 665-670 6 p.

Research output: Contribution to journalArticle

Origin Recognition Complex
Heterochromatin
DNA Replication
Chromatin
Histone Code

Oscillation and light induction of timeless mRNA in the mammalian circadian clock.

Tischkau, S. A., Barnes, J. A., Lin, F. J., Myers, E. M., Barnes, J. W., Meyer-Bernstein, E. L., Hurst, W. J., Burgoon, P. W., Chen, D., Sehgal, A. & Gillette, M. L., Jun 15 1999, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 19, 12

Research output: Contribution to journalArticle

Circadian Clocks
Light
Messenger RNA
Suprachiasmatic Nucleus
Circadian Rhythm

Oscillatory behavior of neutrophils under opposing chemoattractant gradients supports a winner-take-all mechanism

Byrne, M. B., Kimura, Y., Kapoor, A., He, Y., Mattam, K. S., Hasan, K. M., Olson, L. N., Wang, F., Kenis, P. J. A. & Rao, C. V., Jan 21 2014, In : PloS one. 9, 1, e85726.

Research output: Contribution to journalArticle

chemoattractants
Chemotactic Factors
neutrophils
chemotaxis
Neutrophils

Over a century of neuron culture: From the hanging drop to microfluidic devices

Millet, L. J. & Gillette, M. L., Dec 1 2012, In : Yale Journal of Biology and Medicine. 85, 4, p. 501-521 21 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Neurons
Brain
Hydrogels

Overcoming steric hindrances during replication of peripheral heterochromatin

Zhironkina, O. A., Kurchashova, S. Y., Brattseva, A. L., Cherepaninets, V. D., Strelkova, O. S., Belmont, A. S. & Kireev, I. I., Mar 1 2015, In : Cell and Tissue Biology. 9, 2, p. 110-118 9 p.

Research output: Contribution to journalArticle

Heterochromatin
Lamins
Chromatin
Nuclear Lamina
S Phase

Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates

Schiltz, R. L., Mizzen, C. A., Vassilev, A., Cook, R. G., Allis, C. D. & Nakatani, Y., Jan 15 1999, In : Journal of Biological Chemistry. 274, 3, p. 1189-1192 4 p.

Research output: Contribution to journalArticle

Acetylation
Histones
Lysine
Substrates
Chromatin

p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity

Forafonov, F., Toogun, O. A., Grad, I., Suslova, E., Freeman, B. C. & Picard, D., May 1 2008, In : Molecular and cellular biology. 28, 10, p. 3446-3456 11 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Essential Genes
Eukaryota
Saccharomyces cerevisiae
Adenosine Triphosphatases

Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA

Anantharaman, A., Jadaliha, M., Tripathi, V., Nakagawa, S., Hirose, T., Jantsch, M. F., Prasanth, S. G. & Prasanth, K. V., Sep 26 2016, In : Scientific reports. 6, 34043.

Research output: Contribution to journalArticle

RNA
Long Noncoding RNA
Nuclear RNA
Proteasome Endopeptidase Complex
Lighting

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity

Yoon, J. H., De, S., Srikantan, S., Abdelmohsen, K., Grammatikakis, I., Kim, J., Kim, K. M., Noh, J. H., White, E. J. F., Martindale, J. L., Yang, X., Kang, M. J., Wood, W. H., Noren Hooten, N., Evans, M. K., Becker, K. G., Tripathi, V., Prasanth, K. V., Wilson, G. M., Tuschl, T. & 3 others, Ingolia, N. T., Hafner, M. & Gorospe, M., Jan 1 2014, In : Nature communications. 5, 5248.

Research output: Contribution to journalArticle

Ribonucleosides
genome
crosslinking
Immunoprecipitation
Crosslinking

PCNA-mediated stabilization of E3 ligase RFWD3 at the replication fork is essential for DNA replication

Lin, Y. C., Wang, Y., Hsu, R., Giri, S., Wopat, S., Arif, M. K., Chakraborty, A., Kannanganattu, P. K. & Prasanth, S. G., Dec 26 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 52, p. 13282-13287 6 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Proliferating Cell Nuclear Antigen
DNA Replication
Replication Protein A
S Phase

Pdd1p associates with germline-restricted chromatin and a second novel anlagen-enriched protein in developmentally programmed DNA elimination structures

Smothers, J. F., Mizzen, C. A., Tubbert, M. M., Cook, R. G. & Allis, C. D., Dec 17 1997, In : Development. 124, 22, p. 4537-4545 9 p.

Research output: Contribution to journalArticle

Chromatin
DNA
protein
Proteins
Macronucleus

Peptides from purified soybean β-conglycinin inhibit fatty acid synthase by interaction with the thioesterase catalytic domain

Martinez-Villaluenga, C., Rupasinghe, S. G., Schuler, M. A. & Gonzalez De Mejia, E., Mar 1 2010, In : FEBS Journal. 277, 6, p. 1481-1493 13 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Soybeans
Catalytic Domain
Peptides
Inhibitory Concentration 50

Peptidomic analyses of mouse astrocytic cell lines and rat primary cultured astrocytes

Yin, P., Knolhoff, A. M., Rosenberg, H. J., Millet, L. J., Gillette, M. U. & Sweedler, J. V., Aug 3 2012, In : Journal of Proteome Research. 11, 8, p. 3965-3973 9 p.

Research output: Contribution to journalArticle

Astrocytes
Rats
Cells
Cell Line
Peptides

Pervasive combinatorial modification of histone H3 in human cells

Garcia, B. A., Pesavento, J. J., Mizzen, C. A. & Kelleher, N. L., Jun 1 2007, In : Nature Methods. 4, 6, p. 487-489 3 p.

Research output: Contribution to journalArticle

Histones
Cells
Histone Code
Butyrates
Tandem Mass Spectrometry

Phase correlation imaging of unlabeled cell dynamics

Ma, L., Rajshekhar, G., Wang, R., Bhaduri, B., Sridharan, S., Mir, M., Chakraborty, A., Iyer, R., Prasanth, S., Millet, L., Gillette, M. U. & Popescu, G., Sep 12 2016, In : Scientific reports. 6, 32702.

Research output: Contribution to journalArticle

Polymerization
Actins
Time-Lapse Imaging
Fluorescence

Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts

Wang, F., Hansen, R. K., Radisky, D., Yoneda, T., Barcellos-Hoff, M. H., Petersen, O. W., Turley, E. A. & Bissell, M. J., Oct 2 2002, In : Journal of the National Cancer Institute. 94, 19, p. 1494-1503 10 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinases
Integrins
Cell Death
Basement Membrane
Cadherins

Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect

Yoon, M. S., Sun, Y., Arauz, E., Jiang, Y. & Chen, J., Aug 26 2011, In : Journal of Biological Chemistry. 286, 34, p. 29568-29574 7 p.

Research output: Contribution to journalArticle

Tacrolimus Binding Proteins
Phosphatidic Acids
Phosphotransferases
Tacrolimus Binding Protein 1A
Chemical activation

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

Fang, Y., Vilella-Bach, M., Bachmann, R., Flanigan, A. & Chen, J., Nov 30 2001, In : Science. 294, 5548, p. 1942-1945 4 p.

Research output: Contribution to journalArticle

Phosphatidic Acids
Sirolimus
Mitogens
Signal Transduction
Phospholipase D

Phospholipase D1 is an effector of Rheb in the mTOR pathway

Sun, Y., Fang, Y., Yoon, M. S., Zhang, C., Roccio, M., Zwartkruis, F. J., Armstrong, M., Brown, H. A. & Chen, J., Jun 17 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 24, p. 8286-8291 6 p.

Research output: Contribution to journalArticle

Phospholipase D
Sirolimus
Phosphatidic Acids
AMP-Activated Protein Kinases
Monomeric GTP-Binding Proteins

Phosphorylation-dephosphorylation cycle of HP1á governs accurate mitotic progression

Chakraborty, A. & Prasanth, S. G., Jun 1 2014, In : Cell Cycle. 13, 11, p. 1663-1670 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Prometaphase
Mitosis
Chromatin
heterochromatin-specific nonhistone chromosomal protein HP-1

Phosphorylation influences the translation state of FMRP-associated polyribosomes

Ceman, S., O'Donnell, W. T., Reed, M., Patton, S., Pohl, J. & Warren, S. T., Dec 15 2003, In : Human molecular genetics. 12, 24, p. 3295-3305 11 p.

Research output: Contribution to journalArticle

Polyribosomes
Phosphorylation
Serine
Fragile X Mental Retardation Protein
Fragile X Syndrome

Phosphorylation of FMRP inhibits association with Dicer

Cheever, A. & Ceman, S., Mar 1 2009, In : RNA. 15, 3, p. 362-366 5 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Phosphorylation
MicroRNAs
Phospho-Specific Antibodies
Fragile X Syndrome

Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena

Wei, Y., Mizzen, C. A., Cook, R. G., Gorovsky, M. A. & Allis, C. D., Jun 23 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 13, p. 7480-7484 5 p.

Research output: Contribution to journalArticle

Tetrahymena
Meiosis
Mitosis
Histones
Serine

Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal

Dou, Y., Mizzen, C. A., Abrams, M., Allis, C. D. & Gorovsky, M. A., Oct 1999, In : Molecular cell. 4, 4, p. 641-647 7 p.

Research output: Contribution to journalArticle

Histones
Phosphorylation
Gene Expression
Genes
Tetrahymena

Photon-separation to enhance the spatial resolution of pulsed STED microscopy

Tortarolo, G., Sun, Y., Teng, K. W., Ishitsuka, Y., Lanzanó, L., Selvin, P. R., Barbieri, B., Diaspro, A. & Vicidomini, G., Jan 28 2019, In : Nanoscale. 11, 4, p. 1754-1761 8 p.

Research output: Contribution to journalArticle

Stimulated emission
Microscopic examination
Photons
Tuning
Laser beams

pH-sensitive, Ca2+/calmodulin-dependent phosphorylation of unique protein in molluscan nervous system

Gillette, R., Gillette, M. L., Lipeski, L. & Connor, J., Dec 6 1990, In : BBA - General Subjects. 1036, 3, p. 207-212 6 p.

Research output: Contribution to journalArticle

Phosphorylation
Neurology
Calmodulin
Nervous System
Proteins

Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin

Raghuram, N., Strickfaden, H., McDonald, D., Williams, K., Fang, H., Mizzen, C., Hayes, J. J., Th'ng, J. & Hendzel, M. J., Oct 25 2013, In : Journal of Cell Biology. 203, 1, p. 57-71 15 p.

Research output: Contribution to journalArticle

Histones
Chromatin
Phosphorylation
Peptidylprolyl Isomerase
RNA Polymerase II

Pituitary adenylate cyclase activating peptide (PACAP) in the retinohypothalamic tract: A daytime regulator of the biological clock

Hannibal, J., Ding, J. M., Chen, D., Fahrenkrug, J., Larsen, P. J., Gillette, M. L. & Mikkelsen, J. D., Jan 1 1998, In : Annals of the New York Academy of Sciences. 865, p. 197-206 10 p.

Research output: Contribution to journalArticle

Biological Clocks
Adenylyl Cyclases
Clocks
Peptides
Suprachiasmatic Nucleus

Pituitary adenylate cyclase-activating peptide (PACAP) in the retinohypothalamic tract: A potential daytime regulator of the biological clock

Hannibal, J., Ding, J. M., Chen, D., Fahrenkrug, J., Larsen, P. J., Gillette, M. L. & Mikkelsen, J. D., Apr 8 1997, In : Journal of Neuroscience. 17, 7, p. 2637-2644 8 p.

Research output: Contribution to journalArticle

Biological Clocks
Suprachiasmatic Nucleus
Adenylyl Cyclases
Peptides
Pituitary Adenylate Cyclase-Activating Polypeptide Receptors

Pituitary adenylyl cyclase-activating peptide: A pivotal modulator of glutamatergic regulation of the suprachiasmatic circadian clock

Chen, D., Buchanan, G. F., Ding, J. M., Hannibal, J. & Gillette, M. U., Nov 9 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 23, p. 13468-13473 6 p.

Research output: Contribution to journalArticle

Circadian Clocks
Adenylyl Cyclases
Glutamic Acid
Peptides
Suprachiasmatic Nucleus

Plant allelochemicals differentially regulate Helicoverpa zea cytochrome P450 genes

Li, X., Berenbaum, M. R. & Schuler, M. A., Aug 24 2002, In : Insect Molecular Biology. 11, 4, p. 343-351 9 p.

Research output: Contribution to journalArticle

Helicoverpa zea
Pheromones
allelochemicals
cytochrome P-450
midgut

Plant cytochrome P450 monooxygenases

Schuler, M. A., Jan 1 1996, In : Critical Reviews in Plant Sciences. 15, 3, p. 235-284 50 p.

Research output: Contribution to journalArticle

cytochrome P-450
heme
oxygen
active sites
flavoproteins

Plant intron sequences: Evidence for distinct groups of introns

Hanley, B. A. & Schuler, M. A., Jul 25 1988, In : Nucleic acids research. 16, 14, p. 7159-7176 18 p.

Research output: Contribution to journalArticle

Introns
RNA Splice Sites
RNA Splicing
Consensus Sequence
HeLa Cells

PLD1 Regulates mTOR Signaling and Mediates Cdc42 Activation of S6K1

Fang, Y., Park, I. H., Wu, A. L., Du, G., Huang, P., Frohman, M. A., Walker, S. J., Brown, H. A. & Chen, J., Dec 2 2003, In : Current Biology. 13, 23, p. 2037-2044 8 p.

Research output: Contribution to journalArticle

Ribosomal Protein S6 Kinases
Phospholipase D
phospholipase D
Sirolimus
phosphotransferases (kinases)

PLD regulates myoblast differentiation through the mTOR-IGF2 pathway

Yoon, M. S. & Chen, J., Feb 1 2008, In : Journal of cell science. 121, 3, p. 282-289 8 p.

Research output: Contribution to journalArticle

Phospholipase D
Myoblasts
Sirolimus
Muscle Development
Skeletal Myoblasts

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

Liu, H., Radisky, D. C., Wang, F. & Bissell, M. J., Feb 16 2004, In : Journal of Cell Biology. 164, 4, p. 603-612 10 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Phosphatidylinositol 3-Kinases
Epithelial Cells
Breast Neoplasms
Phenotype

Polarization effect on position accuracy of fluorophore localization

Enderlein, J., Toprak, E. & Selvin, P. R., Jan 1 2006, In : Optics Express. 14, 18, p. 8111-8120 10 p.

Research output: Contribution to journalArticle

numerical aperture
polarization
molecules
pixels
position errors

Polypurine-repeat-containing RNAs: A novel class of long non-coding RNA in mammalian cells

Zheng, R., Shen, Z., Tripathi, V., Xuan, Z., Freier, S. M., Bennett, C. F., Prasanth, S. G. & Prasanth, K. V., Nov 1 2010, In : Journal of cell science. 123, 21, p. 3734-3744 11 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
RNA
Nuclear Matrix-Associated Proteins
Telophase
Trinucleotide Repeats

Precise characterization of human histones in the H2A gene family by top down mass spectrometry

Boyne, M. T., Pesavento, J. J., Mizzen, C. A. & Kelleher, N. L., Feb 1 2006, In : Journal of Proteome Research. 5, 2, p. 248-253 6 p.

Research output: Contribution to journalArticle

Gene encoding
Post Translational Protein Processing
HeLa Cells
Histones
Mass spectrometry

Preferential dimethylation of histone H4 lysine 20 by Suv4-20

Yang, H., Pesavento, J. J., Starnes, T. W., Cryderman, D. E., Wallrath, L. L., Kelleher, N. L. & Mizzen, C. A., May 2 2008, In : Journal of Biological Chemistry. 283, 18, p. 12085-12092 8 p.

Research output: Contribution to journalArticle

Histones
Lysine
Methylation
Drosophila
Heterochromatin

Probing cellular protein complexes using single-molecule pull-down

Jain, A., Liu, R., Ramani, B., Arauz, E., Ishitsuka, Y., Ragunathan, K., Park, J., Chen, J., Xiang, Y. K. & Ha, T., May 26 2011, In : Nature. 473, 7348, p. 484-488 5 p.

Research output: Contribution to journalArticle

Proteins
Macromolecular Substances
Tissue Extracts
Cyclic AMP-Dependent Protein Kinases
Fluorescence Microscopy

Probing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution Microscopy

Zhang, R., Fruhwirth, G. O., Coban, O., Barrett, J. E., Burgoyne, T., Lee, S. H., Simonson, P. D., Baday, M., Kholodenko, B. N., Futter, C. E., Ng, T. & Selvin, P. R., Jan 24 2017, In : ACS Nano. 11, 1, p. 249-257 9 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Protein Kinases
Microscopic examination
Mitogen-Activated Protein Kinases
Chemical activation
Anthocidaris
Sea Urchins
Embryonic Structures
Blastomeres
Mesoderm

Prolonged in vivo imaging of Xenopus laevis

Hamilton, P. W. & Henry, J. J., Aug 2014, In : Developmental Dynamics. 243, 8, p. 1011-1019 9 p.

Research output: Contribution to journalArticle

Xenopus laevis
Larva
Anesthetics
Anesthesia
Xenopus

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

Chaudhary, R., Gryder, B., Woods, W. S., Subramanian, M., Jones, M. F., Li, X. L., Jenkins, L. M., Shabalina, S. A., Mo, M., Dasso, M., Yang, Y., Wakefield, L. M., Zhu, Y., Frier, S. M., Moriarity, B. S., Prasanth, K. V., Perez-Pinera, P. & Lal, A., Jun 5 2017, In : eLife. 6, e23244.

Research output: Contribution to journalArticle

Long Noncoding RNA
Untranslated RNA
Colorectal Neoplasms
Cells
DNA Damage

Protein kinase G type II is required for night-to-day progression of the mammalian circadian clock

Tischkau, S. A., Mitchell, J. W., Pace, L. A., Barnes, J. W., Barnes, J. A. & Gillette, M. L., Aug 19 2004, In : Neuron. 43, 4, p. 539-549 11 p.

Research output: Contribution to journalArticle

Cyclic GMP-Dependent Protein Kinases
Circadian Clocks
Messenger RNA
Suprachiasmatic Nucleus
Oligodeoxyribonucleotides

Protein phosphatase 2A regulates MPF activity and sister chromatid cohesion in budding yeast

Minshull, J., Straight, A., Rudner, A. D., Dernburg, A. F., Belmont, A. & Murray, A. W., Dec 1996, In : Current Biology. 6, 12, p. 1609-1620 12 p.

Research output: Contribution to journalArticle

maturation-promoting factor
Maturation-Promoting Factor
Protein Phosphatase 2
phosphoprotein phosphatase
Saccharomycetales

Psf2 plays important roles in normal eye development in Xenopus laevis

Walter, B. E., Perry, K. J., Fukui, L., Malloch, E. L., Wever, J. & Henry, J. J., May 19 2008, In : Molecular Vision. 14, p. 906-921 16 p.

Research output: Contribution to journalArticle

Xenopus laevis
Lenses
Morpholinos
Retina
Embryonic Structures

PSIP1/p75 promotes tumorigenicity in breast cancer cells by promoting the transcription of cell cycle genes

Singh, D. K., Gholamalamdari, O., Jadaliha, M., Li, X. L., Lin, Y. C., Zhang, Y., Guang, S., Hashemikhabir, S., Tiwari, S., Zhu, Y. J., Khan, A., Thomas, A., Chakraborty, A., Macias, V., Balla, A. K., Bhargava, R., Janga, S. C., Ma, J., Prasanth, S. G., Lal, A. & 1 others, Kannanganattu, P. K., Oct 1 2017, In : Carcinogenesis. 38, 10, p. 966-975 10 p., bgx062.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
cdc Genes
Breast Neoplasms
RNA Polymerase II
Cell Line

Purification and Analyses of Histone H1 Variants and H1 Posttranslational Modifications

Mizzen, C. A., Feb 4 2004, In : Methods in enzymology. 375, p. 278-297 20 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Biochemistry
Phosphorylation
Poly(ADP-ribose) Polymerases
Ubiquitin