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Identification of key regulatory pathways of myeloid differentiation using an mESC-based karyotypically normal cell model

Li, D., Yang, H., Nan, H., Liu, P., Pang, S., Zhao, Q., Karni, R., Kamps, M. P., Xu, Y., Zhou, J., Wiedmer, T., Sims, P. J. & Wang, F., Dec 6 2012, In : Blood. 120, 24, p. 4712-4719 8 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Stem cells
Karyotyping
Estrogens
Neutrophils

Identification of a novel nuclear factor-binding site in the Pisum sativum sad gene promoters

Gittins, J. R., Schuler, M. A. & Strid, Å., Apr 12 2002, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1574, 3, p. 231-244 14 p.

Research output: Contribution to journalArticle

Peas
Genes
Binding Sites
Transcription
DNA

Identification of a compound origin of replication at the HMR-E locus in Saccharomyces cerevisiae

Hurst, S. T. & Rivier, D. H., Feb 12 1999, In : Journal of Biological Chemistry. 274, 7, p. 4155-4159 5 p.

Research output: Contribution to journalArticle

Replication Origin
Yeast
Saccharomyces cerevisiae
Yeasts
Viverridae

Identification and mutation of phosphorylation sites in a linker histone. Phosphorylation of macronuclear H1 is not essential for viability in Tetrahymena

Mizzen, C. A., Dou, Y., Liu, Y., Cook, R. G., Gorovsky, M. A. & Allist, C. D., May 21 1999, In : Journal of Biological Chemistry. 274, 21, p. 14533-14536 4 p.

Research output: Contribution to journalArticle

Tetrahymena
Phosphorylation
Histones
Mutation
Macronucleus

Identification and characterization of topoisomerase II inhibitory peptides from soy protein hydrolysates

Wang, W., Rupasinghe, S. G., Schuler, M. A. & De Mejia, E. G., Aug 13 2008, In : Journal of Agricultural and Food Chemistry. 56, 15, p. 6267-6277 11 p.

Research output: Contribution to journalArticle

Protein Hydrolysates
DNA topoisomerase (ATP-hydrolysing)
Type II DNA Topoisomerase
Soybean Proteins
peptides

Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp

Stetler, A., Winograd, C., Sayegh, J., Cheever, A., Patton, E., Zhang, X., Clarke, S. & Ceman, S., Jan 1 2006, In : Human molecular genetics. 15, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Arginine
Methylation
RNA
Glycine

Identification and characterization of a seven transmembrane hormone receptor using differential display

Lin, H. H., Stubbs, L. J. & Mucenski, M. L., May 1 1997, In : Genomics. 41, 3, p. 301-308 8 p.

Research output: Contribution to journalArticle

Hormones
Epidermal Growth Factor
Genes
Hematopoiesis
Complementary DNA
Origin Recognition Complex
Heterochromatin
Protein Binding
Chromatin
Proteins

Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain

Sriram, Osipiuk, J., Freeman, B. C., Morimoto, R. I. & Joachimiak, A., Jan 1 1997, In : Structure. 5, 3, p. 403-414 12 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Adenosine Triphosphatases
Ions
Calcium
Adenosine Triphosphate

Hsp90 and p23 Molecular Chaperones Control Chromatin Architecture by Maintaining the Functional Pool of the RSC Chromatin Remodeler

Echtenkamp, F. J., Gvozdenov, Z., Adkins, N. L., Zhang, Y., Lynch-Day, M., Watanabe, S., Peterson, C. L. & Freeman, B. C., Dec 1 2016, In : Molecular cell. 64, 5, p. 888-899 12 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Nucleosomes
Chromatin
Life Cycle Stages
Proteolysis

HSP70 transgene directed motion to nuclear speckles facilitates heat shock activation

Khanna, N., Hu, Y. & Belmont, A. S., May 19 2014, In : Current Biology. 24, 10, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

Speckle
Transgenes
transgenes
heat stress
Shock

Hsp70 gene association with nuclear speckles is Hsp70 promoter specific

Hu, Y., Plutz, M. & Belmont, A. S., Nov 15 2010, In : Journal of Cell Biology. 191, 4, p. 711-719 9 p.

Research output: Contribution to journalArticle

HSP70 Heat-Shock Proteins
Transgenes
Genes
Small Heat-Shock Proteins
Bacterial Artificial Chromosomes

How myosin VI coordinates its heads during processive movement

Sweeney, H. L., Park, H., Zong, A. B., Yang, Z., Selvin, P. R. & Rosenfeld, S. S., Jun 6 2007, In : EMBO Journal. 26, 11, p. 2682-2692 11 p.

Research output: Contribution to journalArticle

Head
Adenosine Diphosphate
Actins
Myosin Type V
Kinesin
Honey
Bees
Immunity
Up-Regulation
Pollen

Honey bee neurogenomic responses to affiliative and agonistic social interactions

Shpigler, H. Y., Saul, M. C., Murdoch, E. E., Corona, F., Cash-Ahmed, A. C., Seward, C. H., Chandrasekaran, S., Stubbs, L. J. & Robinson, G. E., Jan 2019, In : Genes, Brain and Behavior. 18, 1, e12509.

Research output: Contribution to journalArticle

Honey
Bees
Interpersonal Relations
Nursing
Mushroom Bodies

Homology of ciliary bands in Spiralian Trochophores

Henry, J. Q., Hejnol, A., Perry, K. J. & Martindale, M. Q., Dec 1 2007, In : Integrative and comparative biology. 47, 6, p. 865-871 7 p.

Research output: Contribution to journalArticle

larvae
phylogeny
Annelida
molluscs
locomotion
Myosin Type II
Myosin Subfragments
Energy Transfer
Myosins
Head

hnRNP G: Sequence and characterization of a glycosylated RNA-binding protein

Soulard, M., Valle, V. D., Siomi, M. C., Pinol-roma, S., Codogno, P., Bauvy, C., Bellini, M., Lacroix, J. C., Monod, G., Dreyfuss, G. & Larsen, C. J., Sep 11 1993, In : Nucleic acids research. 21, 18, p. 4210-4217 8 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
RNA-Binding Proteins
Plant RNA
Acetylglucosamine
Nuclear Proteins

HMR-I is an origin of replication and a silencer in Saccharomyces cerevisiae

Rivier, D. H., Ekena, J. L. & Rine, J., Feb 1999, In : Genetics. 151, 2, p. 521-529 9 p.

Research output: Contribution to journalArticle

Replication Origin
Saccharomyces cerevisiae
Plasmids

Histones in transit: Cytosolic histone complexes and diacetylation of H4 during nucleosome assembly in human cells

Chang, L., Loranger, S. S., Mizzen, C., Ernst, S. G., Allis, C. D. & Annunziato, A. T., Jan 21 1997, In : Biochemistry. 36, 3, p. 469-480 12 p.

Research output: Contribution to journalArticle

Acetylation
Nucleosomes
Histone Acetyltransferases
Histones
Cells

Histone Modifications Depict an Aberrantly Heterochromatinized FMR1 Gene in Fragile X Syndrome

Coffee, B., Zhang, F., Ceman, S., Warren, S. T. & Reines, D., Jan 1 2002, In : American Journal of Human Genetics. 71, 4, p. 923-932 10 p.

Research output: Contribution to journalArticle

Histone Code
Fragile X Syndrome
Histones
Methylation
Lysine

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

Hsiao, K. Y. & Mizzen, C. A., Jun 1 2013, In : Journal of Molecular Cell Biology. 5, 3, p. 157-165 9 p.

Research output: Contribution to journalArticle

Histones
DNA Damage
Methyltransferases
Acetylation
Histone Deacetylase Inhibitors

Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II

Zheng, Y., John, S., Pesavento, J. J., Schultz-Norton, J. R., Schiltz, R. L., Baek, S., Nardulli, A. M., Hager, G. L., Kelleher, N. L. & Mizzen, C. A., May 3 2010, In : Journal of Cell Biology. 189, 3, p. 407-415 9 p.

Research output: Contribution to journalArticle

RNA Polymerase I
RNA Polymerase II
Interphase
Histones
Phosphorylation

Histone H1 and H3 dephosphorylation are differentially regulated by radiation-induced signal transduction pathways

Guo, C. Y., Mizzen, C., Wang, Y. & Larner, J. M., Oct 15 2000, In : Cancer Research. 60, 20, p. 5667-5672 6 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Histones
Signal Transduction
Radiation
Ataxia Telangiectasia

Histone acetyltransferases: Preparation of substrates and assay procedures

Mizzen, C. A., Brownell, J. E., Cook, R. G. & Allis, C. D., Jan 1 1999, In : Methods in enzymology. 304, p. 675-696 22 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Assays
Substrates

Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers

Iizuka, M., Takahashi, Y., Mizzen, C. A., Cook, R. G., Fujita, M., Allis, C. D., Frierson, H. F., Fukusato, T. & Smith, M. M., May 1 2009, In : Gene. 436, 1-2, p. 108-114 7 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
DNA Replication
Chromatin
Neoplasms
Replication Origin

Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation

Wang, L., Mizzen, C. A., Ying, C., Candau, R., Barlev, N., Brownell, J., Allis, C. D. & Berger, S. L., Jan 1 1997, In : Molecular and cellular biology. 17, 1, p. 519-527 9 p.

Research output: Contribution to journalArticle

Histone Acetyltransferases
Transcriptional Activation
Yeasts
Growth
Nucleosomes

High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy

Rupasinghe, S. G., Duan, H., Frericks Schmidt, H. L., Berthold, D. A., Rienstra, C. M. & Schuler, M. A., Dec 1 2007, In : Biochimica et Biophysica Acta - Biomembranes. 1768, 12, p. 3061-3070 10 p.

Research output: Contribution to journalArticle

Mixed Function Oxygenases
Cytochrome P-450 Enzyme System
Nuclear magnetic resonance spectroscopy
Purification
Magnetic Resonance Spectroscopy

High-resolution fate map of the snail Crepidula fornicata: The origins of ciliary bands, nervous system, and muscular elements

Hejnol, A., Martindale, M. Q. & Henry, J. Q., May 1 2007, In : Developmental Biology. 305, 1, p. 63-76 14 p.

Research output: Contribution to journalArticle

Snails
Cell Lineage
Nervous System
Blastomeres
Gastropoda

High-pressure treatment of polytene chromosomes improves structural resolution

Novikov, D. V., Kireev, I. & Belmont, A. S., Jun 1 2007, In : Nature Methods. 4, 6, p. 483-485 3 p.

Research output: Contribution to journalArticle

Polytene Chromosomes
Chromosomes
Cytology
Pressure
Cell Biology

High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1

Qu, Q., Li, D., Louis, K. R., Li, X., Yang, H., Sun, Q., Crandall, S. R., Tsang, S., Zhou, J., Cox, C. L., Cheng, J. & Wang, F., Mar 13 2014, In : Nature communications. 5, 3449.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
stem cells
Motor Neurons
Stem cells
neurons

High-efficiency induction of neural conversion in human ESCs and human induced pluripotent stem cells with a single chemical inhibitor of transforming growth factor beta superfamily receptors

Zhou, J., Su, P., Li, D., Tsang, S., Duan, E. & Wang, F., Oct 1 2010, In : Stem Cells. 28, 10, p. 1741-1750 10 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta Receptors
Induced Pluripotent Stem Cells
Efficiency
Morphogenesis
Activins

Hereditary diabetes insipidus: an immunohistochemical study of the hypothalamus and pituitary gland

Bergeron, C., Kovacs, K., Ezrin, C. & Mizzen, C., Feb 1 1991, In : Acta Neuropathologica. 81, 3, p. 345-348 4 p.

Research output: Contribution to journalArticle

Diabetes Insipidus
Pituitary Gland
Vasopressins
Hypothalamus
Posterior Pituitary Gland

Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures

Yu, W., O'Brien, L. E., Wang, F., Bourne, H., Mostov, K. E. & Zegers, M. M. P., Feb 1 2003, In : Molecular biology of the cell. 14, 2, p. 748-763 16 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Morphogenesis
Epithelial Cells
rho-Associated Kinases
Madin Darby Canine Kidney Cells

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

Sun, Z., Miller, R. A., Patel, R. T., Chen, J., Dhir, R., Wang, H., Zhang, D., Graham, M. J., Unterman, T. G., Shulman, G. I., Sztalryd, C., Bennett, M. J., Ahima, R. S., Birnbaum, M. J. & Lazar, M. A., Jun 1 2012, In : Nature Medicine. 18, 6, p. 934-942 9 p.

Research output: Contribution to journalArticle

Gluconeogenesis
Lipids
Liver
Insulin
Insulin Resistance

Helicoverpa zea CYP6B8 and CYP321A1: Different molecular solutions to the problem of metabolizing plant toxins and insecticides

Rupasinghe, S. G., Wen, Z., Chiu, T. L. & Schuler, M. A., Dec 1 2007, In : Protein Engineering, Design and Selection. 20, 12, p. 615-624 10 p.

Research output: Contribution to journalArticle

Insecticides
Mixed Function Oxygenases
Zea mays
Oxygen
Molecules

Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1

Kim, I. J., Lee, J., Oh, S. J., Yoon, M. S., Jang, S. S., Holland, R. L., Reno, M. L., Hamad, M. N., Maeda, T., Chung, H. J., Chen, J. & Blanke, S. R., May 9 2018, In : Cell Host and Microbe. 23, 5, p. 583-593.e8

Research output: Contribution to journalArticle

Helicobacter Infections
Helicobacter pylori
Autophagy
Amino Acids
Mitochondria

Heightened susceptibility to chronic gastritis, hyperplasia and metaplasia in Kcnq1 mutant mice

Elso, C. M., Lu, X., Culiat, C. T., Rutledge, J. C., Cacheiro, N. L. A., Generoso, W. M. & Stubbs, L. J., Nov 15 2004, In : Human molecular genetics. 13, 22, p. 2813-2821 9 p.

Research output: Contribution to journalArticle

Metaplasia
Gastritis
Hyperplasia
Helicobacter Infections
Mucins

Guiding neuron development with planar surface gradients of substrate cues deposited using microfluidic devices

Millet, L. J., Stewart, M. E., Nuzzo, R. G. & Gillette, M. U., 2010, In : Lab on a chip. 10, 12, p. 1525-1535 11 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Neurons
Cues
Laminin

Growth differentiation factor-15 encodes a novel microRNA 3189 that functions as a potent regulator of cell death

Jones, M. F., Ling Li, X., Subramanian, M., Shabalina, S. A., Hara, T., Zhu, Y., Huang, J., Yang, Y., Wakefield, L. M., Prasanth, K. V. & Lal, A., Oct 9 2015, In : Cell Death and Differentiation. 22, 10, p. 1641-1653 13 p.

Research output: Contribution to journalArticle

Growth Differentiation Factor 15
MicroRNAs
Primates
Cell Death
Apoptosis

Gravity persistent signal 1 (GPS1) reveals novel cytochrome P450s involved in Gravitropism

Withers, J. C., Shipp, M. J., Rupasinghe, S. G., Sukumar, P., Schuler, M. A., Muday, G. K. & Wyatt, S. E., Jan 1 2013, In : American journal of botany. 100, 1, p. 183-193 11 p.

Research output: Contribution to journalArticle

Gravitropism
gravitropism
Gravitation
Cytochromes
cytochromes

Graphene oxide substrates with N-cadherin stimulates neuronal growth and intracellular transport

Qin, E. C., Kandel, M. E., Liamas, E., Shah, T. B., Kim, C., Kaufman, C. D., Zhang, Z. J., Popescu, G., Gillette, M. L., Leckband, D. E. & Kong, H. J., May 2019, In : Acta Biomaterialia. 90, p. 412-423 12 p.

Research output: Contribution to journalArticle

Graphite
Cadherins
Oxides
Graphene
Neurons

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling

Zhang, C., Wendel, A. A., Keogh, M. R., Harris, T. E., Chen, J. & Coleman, R. A., Jan 31 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 5, p. 1667-1672 6 p.

Research output: Contribution to journalArticle

Acyltransferases
Phosphatidic Acids
Insulin
Hepatocytes
Diglycerides

Glutathione-S-transferase μ and theta gene polymorphisms as new risk factors of atopic bronchial asthma

Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G. & Bourne, H. R., Jan 1 2002, In : Journal of Molecular Medicine. 80, 1, p. 39-43 5 p.

Research output: Contribution to journalArticle

Glutathione Transferase
Asthma
Genes
Phase I Metabolic Detoxication
isoleucylvaline

Global Functional Map of the p23 Molecular Chaperone Reveals an Extensive Cellular Network

Echtenkamp, F. J., Zelin, E., Oxelmark, E., Woo, J. I., Andrews, B. J., Garabedian, M. & Freeman, B. C., Jul 22 2011, In : Molecular cell. 43, 2, p. 229-241 13 p.

Research output: Contribution to journalArticle

Molecular Chaperones
Yeasts
Validation Studies
Mutagens
Ribosomes

Global assessment of combinatorial post-translational modification of core histones in yeast using contemporary mass spectrometry: LYS4 trimethylation correlates with degree of acetylation on the same H3 tail

Jiang, L., Smith, J. N., Anderson, S. L., Ma, P., Mizzen, C. A. & Kelleher, N. L., Sep 21 2007, In : Journal of Biological Chemistry. 282, 38, p. 27923-27934 12 p.

Research output: Contribution to journalArticle

Acetylation
Post Translational Protein Processing
Histones
Yeast
Mass spectrometry

Glacier moraine formation-mimicking colloidal particle assembly in microchanneled, bioactive hydrogel for guided vascular network construction

Lee, M. K., Rich, M. H., Shkumatov, A., Jeong, J. H., Boppart, M. D., Bashir, R., Gillette, M. U., Lee, J. & Kong, H., Jan 1 2015, In : Advanced Healthcare Materials. 4, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

Ice Cover
Glaciers
Hydrogel
Microchannels
Hydrogels

GFP tagging of budding yeast chromosomes reveals that protein-protein interactions can mediate sister chromatid cohesion

Straight, A. F., Belmont, A. S., Robinett, C. C. & Murray, A. W., Dec 1996, In : Current Biology. 6, 12, p. 1599-1608 10 p.

Research output: Contribution to journalArticle

Saccharomycetales
Chromatids
chromatids
protein-protein interactions
Chromosomes

Genomic organization and expressed sequences of the mouse extended h-2k region

Lai, F., Stubbs, L., Lehrach, H., Huang, Y., Yeom, Y. & Artzt, K., Sep 15 1994, In : Genomics. 23, 2, p. 338-343 6 p.

Research output: Contribution to journalArticle

Major Histocompatibility Complex
Lethal Genes
Genes
Restriction Mapping
Immune System

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax

Fang, X., Nevo, E., Han, L., Levanon, E. Y., Zhao, J., Avivi, A., Larkin, D., Jiang, X., Feranchuk, S., Zhu, Y., Fishman, A., Feng, Y., Sher, N., Xiong, Z., Hankeln, T., Huang, Z., Gorbunova, V., Zhang, L., Zhao, W., Wildman, D. E. & 33 others, Xiong, Y., Gudkov, A., Zheng, Q., Rechavi, G., Liu, S., Bazak, L., Chen, J., Knisbacher, B. A., Lu, Y., Shams, I., Gajda, K., Farré, M., Kim, J., Lewin, H. A., Ma, J., Band, M., Bicker, A., Kranz, A., Mattheus, T., Schmidt, H., Seluanov, A., Azpurua, J., McGowen, M. R., Ben Jacob, E., Li, K., Peng, S., Zhu, X., Liao, X., Li, S., Krogh, A., Zhou, X., Brodsky, L. & Wang, J., Jun 3 2014, In : Nature communications. 5, 3966.

Research output: Contribution to journalArticle

Spalax
Mole Rats
genome
rats
Rats