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2015

Review and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channel

Jackson, J. B., Leung, J. H., Stout, C. D., Schurig-Briccio, L. A. & Gennis, R. B., Jul 20 2015, In : FEBS Letters. 589, 16, p. 2027-2033 7 p.

Research output: Contribution to journalReview article

TCR affinity for p/MHC formed by tumor antigens that are self-proteins: Impact on efficacy and toxicity

Stone, J. D., Harris, D. T. & Kranz, D. M., Apr 1 2015, In : Current Opinion in Immunology. 33, p. 16-22 7 p.

Research output: Contribution to journalReview article

2014

Multitarget drug discovery for tuberculosis and other infectious diseases

Li, K., Schurig-Briccio, L. A., Feng, X., Upadhyay, A., Pujari, V., Lechartier, B., Fontes, F. L., Yang, H., Rao, G., Zhu, W., Gulati, A., No, J. H., Cintra, G., Bogue, S., Liu, Y. L., Molohon, K., Orlean, P., Mitchell, D. A., Freitas-Junior, L., Ren, F. & 8 others, Sun, H., Jiang, T., Li, Y., Guo, R. T., Cole, S. T., Gennis, R. B., Crick, D. C. & Oldfield, E., Apr 10 2014, In : Journal of Medicinal Chemistry. 57, 7, p. 3126-3129 4 p.

Research output: Contribution to journalReview article

Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigens

Sharma, P., Wang, N. & Kranz, D. M., Feb 13 2014, In : Toxins. 6, 2, p. 556-574 19 p.

Research output: Contribution to journalReview article

Structure and mechanism of lanthipeptide biosynthetic enzymes

van der Donk, W. A. & Nair, S. K., Dec 1 2014, In : Current Opinion in Structural Biology. 29, p. 58-66 9 p.

Research output: Contribution to journalReview article

The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal

Cronan, J. E., Jun 1 2014, In : Biochemical Journal. 460, 2, p. 157-163 7 p.

Research output: Contribution to journalReview article

2013

Insights into the evolution of lanthipeptide biosynthesis

Yu, Y., Zhang, Q. & Van Der Donk, W. A., Nov 1 2013, In : Protein Science. 22, 11, p. 1478-1489 12 p.

Research output: Contribution to journalReview article

Optimizations to achieve high-level expression of cytochrome P450 proteins using Escherichia coli expression systems

Zelasko, S., Palaria, A. & Das, A., Nov 1 2013, In : Protein Expression and Purification. 92, 1, p. 77-87 11 p.

Research output: Contribution to journalReview article

Phosphonate biosynthesis and catabolism: A treasure trove of unusual enzymology

Peck, S. C. & van der Donk, W. A., Aug 1 2013, In : Current Opinion in Chemical Biology. 17, 4, p. 580-588 9 p.

Research output: Contribution to journalReview article

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Arnison, P. G., Bibb, M. J., Bierbaum, G., Bowers, A. A., Bugni, T. S., Bulaj, G., Camarero, J. A., Campopiano, D. J., Challis, G. L., Clardy, J., Cotter, P. D., Craik, D. J., Dawson, M., Dittmann, E., Donadio, S., Dorrestein, P. C., Entian, K. D., Fischbach, M. A., Garavelli, J. S., Göransson, U. & 45 others, Gruber, C. W., Haft, D. H., Hemscheidt, T. K., Hertweck, C., Hill, C., Horswill, A. R., Jaspars, M., Kelly, W. L., Klinman, J. P., Kuipers, O. P., Link, A. J., Liu, W., Marahiel, M. A., Mitchell, D. A., Moll, G. N., Moore, B. S., Müller, R., Nair, S. K., Nes, I. F., Norris, G. E., Olivera, B. M., Onaka, H., Patchett, M. L., Piel, J., Reaney, M. J. T., Rebuffat, S., Ross, R. P., Sahl, H. G., Schmidt, E. W., Selsted, M. E., Severinov, K., Shen, B., Sivonen, K., Smith, L., Stein, T., Süssmuth, R. D., Tagg, J. R., Tang, G. L., Truman, A. W., Vederas, J. C., Walsh, C. T., Walton, J. D., Wenzel, S. C., Willey, J. M. & Van Der Donk, W. A., Jan 2013, In : Natural Product Reports. 30, 1, p. 108-160 53 p.

Research output: Contribution to journalReview article

Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies

Stone, J. D. & Kranz, D. M., Sep 16 2013, In : Frontiers in immunology. 4, AUG, Article 244.

Research output: Contribution to journalReview article

Role of the Helicobacter pylori-Induced inflammatory response in the development of gastric cancer

Lamb, A. & Chen, L. F., Mar 1 2013, In : Journal of Cellular Biochemistry. 114, 3, p. 491-497 7 p.

Research output: Contribution to journalReview article

2012

A novel type of allosteric regulation: Functional cooperativity in monomeric proteins

Denisov, I. G. & Sligar, S. G., Mar 15 2012, In : Archives of Biochemistry and Biophysics. 519, 2, p. 91-102 12 p.

Research output: Contribution to journalReview article

Discovery, biosynthesis, and engineering of lantipeptides

Knerr, P. J. & van der Donk, W. A., Jul 1 2012, In : Annual review of biochemistry. 81, p. 479-505 27 p.

Research output: Contribution to journalReview article

Genome of papaya, a fast growing tropical fruit tree

Ming, R., Yu, Q., Moore, P. H., Paull, R. E., Chen, N. J., Wang, M. L., Zhu, Y. J., Schuler, M. A., Jiang, J. & Paterson, A. H., Jun 1 2012, In : Tree Genetics and Genomes. 8, 3, p. 445-462 18 p.

Research output: Contribution to journalReview article

Insect P450s: Mounted for battle in their war against toxins

Schuler, M. A., Sep 1 2012, In : Molecular ecology. 21, 17, p. 4157-4159 3 p.

Research output: Contribution to journalReview article

Microcin C: Biosynthesis and mechanisms of bacterial resistance

Severinov, K. & Nair, S. K., Feb 1 2012, In : Future Microbiology. 7, 2, p. 281-289 9 p.

Research output: Contribution to journalReview article

Polyphosphate: An ancient molecule that links platelets, coagulation, and inflammation

Morrissey, J. H., Choi, S. H. & Smith, S. A., Jun 21 2012, In : Blood. 119, 25, p. 5972-5979 8 p.

Research output: Contribution to journalReview article

Proton transfer in ba 3 cytochrome c oxidase from Thermus thermophilus

Von Ballmoos, C., Ädelroth, P., Gennis, R. B. & Brzezinski, P., Apr 1 2012, In : Biochimica et Biophysica Acta - Bioenergetics. 1817, 4, p. 650-657 8 p.

Research output: Contribution to journalReview article

Quorum sensing: How bacteria can coordinate activity and synchronize their response to external signals?

Li, Z. & Nair, S. K., Oct 1 2012, In : Protein Science. 21, 10, p. 1403-1417 15 p.

Research output: Contribution to journalReview article

Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

Chan, J., Dodani, S. C. & Chang, C. J., Dec 1 2012, In : Nature Chemistry. 4, 12, p. 973-984 12 p.

Research output: Contribution to journalReview article

Reconstitution of respiratory oxidases in membrane nanodiscs for investigation of proton-coupled electron transfer

Näsvik Öjemyr, L., Von Ballmoos, C., Gennis, R. B., Sligar, S. G. & Brzezinski, P., Mar 9 2012, In : FEBS Letters. 586, 5, p. 640-645 6 p.

Research output: Contribution to journalReview article

2011

Closing in on complete pathways of biotin biosynthesis

Lin, S. & Cronan, J. E., Jun 1 2011, In : Molecular BioSystems. 7, 6, p. 1811-1821 11 p.

Research output: Contribution to journalReview article

Cytochromes P450 in nanodiscs

Denisov, I. G. & Sligar, S. G., Jan 1 2011, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1814, 1, p. 223-229 7 p.

Research output: Contribution to journalReview article

Functional consequences of developmentally regulated alternative splicing

Kalsotra, A. & Cooper, T. A., Oct 1 2011, In : Nature Reviews Genetics. 12, 10, p. 715-729 15 p.

Research output: Contribution to journalReview article

Genome mining for ribosomally synthesized natural products

Velásquez, J. E. & Van der Donk, W. A., Feb 1 2011, In : Current Opinion in Chemical Biology. 15, 1, p. 11-21 11 p.

Research output: Contribution to journalReview article

Nanoscale studies of protein-membrane interactions in blood clotting

Morrissey, J. H., Tajkhorshid, E. & Rienstra, C. M., Jul 1 2011, In : Journal of Thrombosis and Haemostasis. 9, 1 S, p. 162-167 6 p.

Research output: Contribution to journalReview article

P450s in plant-insect interactions

Schuler, M. A., Jan 1 2011, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1814, 1, p. 36-45 10 p.

Research output: Contribution to journalReview article

Proteasome activators

Stadtmueller, B. M. & Hill, C. P., Jan 7 2011, In : Molecular cell. 41, 1, p. 8-19 12 p.

Research output: Contribution to journalReview article

Spectroscopic features of cytochrome P450 reaction intermediates

Luthra, A., Denisov, I. G. & Sligar, S. G., Mar 1 2011, In : Archives of Biochemistry and Biophysics. 507, 1, p. 26-35 10 p.

Research output: Contribution to journalReview article

Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway

Cronan, J. E. & Lin, S., Jun 1 2011, In : Current Opinion in Chemical Biology. 15, 3, p. 407-413 7 p.

Research output: Contribution to journalReview article

The cytochrome bd respiratory oxygen reductases

Borisov, V. B., Gennis, R. B., Hemp, J. & Verkhovsky, M. I., Nov 1 2011, In : Biochimica et Biophysica Acta - Bioenergetics. 1807, 11, p. 1398-1413 16 p.

Research output: Contribution to journalReview article

The enzyme function initiative

Gerlt, J. A., Allen, K. N., Almo, S. C., Armstrong, R. N., Babbitt, P. C., Cronan, J. E., Dunaway-Mariano, D., Imker, H. J., Jacobson, M. P., Minor, W., Poulter, C. D., Raushel, F. M., Sali, A., Shoichet, B. K. & Sweedler, J. V., Nov 22 2011, In : Biochemistry. 50, 46, p. 9950-9962 13 p.

Research output: Contribution to journalReview article

2010

Capturing functional motions of membrane channels and transporters with molecular dynamics simulation

Shaikh, S. A., Wen, P. C., Enkavi, G., Huang, Z. & Tajkhorshid, E., Dec 1 2010, In : Journal of Computational and Theoretical Nanoscience. 7, 12, p. 2481-2500 20 p.

Research output: Contribution to journalReview article

Exploring transmembrane diffusion pathways with molecular dynamics

Wang, Y., Shaikh, S. A. & Tajkhorshid, E., Jun 2010, In : Physiology. 25, 3, p. 142-154 13 p.

Research output: Contribution to journalReview article

Follow the leader: The use of leader peptides to guide natural product biosynthesis

Oman, T. J. & Van Der Donk, W. A., Jan 2010, In : Nature chemical biology. 6, 1, p. 9-18 10 p.

Research output: Contribution to journalReview article

Membrane protein assembly into Nanodiscs

Bayburt, T. H. & Sligar, S. G., May 1 2010, In : FEBS Letters. 584, 9, p. 1721-1727 7 p.

Research output: Contribution to journalReview article

Posttranslational modifications of NF-κB: Another layer of regulation for NF-κB signaling pathway

Huang, B., Yang, X. D., Lamb, A. & Chen, L-F., Sep 1 2010, In : Cellular Signalling. 22, 9, p. 1282-1290 9 p.

Research output: Contribution to journalReview article

Protein-Phospholipid interactions in blood clotting

Morrissey, J. H., Davis-Harrison, R. L., Tavoosi, N., Ke, K., Pureza, V., Boettcher, J. M., Clay, M. C., Rienstra, C., Ohkubo, Y. Z., Pogorelov, T. V. & Tajkhorshid, E., Apr 1 2010, In : Thrombosis Research. 125, SUPPL. 1, p. S23-S25

Research output: Contribution to journalReview article

Substrate activation by iron superoxo intermediates

van der Donk, W. A., Krebs, C. & Bollinger, J. M., Dec 1 2010, In : Current Opinion in Structural Biology. 20, 6, p. 673-683 11 p.

Research output: Contribution to journalReview article

The balance between pre- and post-transfer editing in tRNA synthetases

Martinis, S. A. & Boniecki, M. T., Jan 21 2010, In : FEBS Letters. 584, 2, p. 455-459 5 p.

Research output: Contribution to journalReview article

2009

Antigen processing and presentation: TAPping into ABC transporters

Procko, E. & Gaudet, R., Feb 1 2009, In : Current Opinion in Immunology. 21, 1, p. 84-91 8 p.

Research output: Contribution to journalReview article

Biosynthesis of phosphonic and phosphinic acid natural products

Metcalf, W. W. & van der Donk, W. A., Jul 27 2009, In : Annual review of biochemistry. 78, p. 65-94 30 p.

Research output: Contribution to journalReview article

Chapter 11 Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs

Ritchie, T. K., Grinkova, Y. V., Bayburt, T. H., Denisov, I. G., Zolnerciks, J. K., Atkins, W. M. & Sligar, S. G., Dec 14 2009, In : Methods in enzymology. 464, C, p. 211-231 21 p.

Research output: Contribution to journalReview article

Cooperative properties of cytochromes P450

Denisov, I. G., Frank, D. J. & Sligar, S. G., Nov 1 2009, In : Pharmacology and Therapeutics. 124, 2, p. 151-167 17 p.

Research output: Contribution to journalReview article

Diversity in enoyl-acyl carrier protein reductases

Massengo-Tiassé, R. P. & Cronan, J. E., Jan 1 2009, In : Cellular and Molecular Life Sciences. 66, 9, p. 1507-1517 11 p.

Research output: Contribution to journalReview article

Enzyme (re)design: lessons from natural evolution and computation

Gerlt, J. A. & Babbitt, P. C., Feb 1 2009, In : Current Opinion in Chemical Biology. 13, 1, p. 10-18 9 p.

Research output: Contribution to journalReview article

Methylation, a new epigenetic mark for protein stability

Yang, X. D., Lamb, A. & Chen, L. F., Oct 1 2009, In : Epigenetics. 4, 7, p. 429-433 5 p.

Research output: Contribution to journalReview article