Research Output

Filter
Review article
Review article

Review and Hypothesis. New insights into the reaction mechanism of transhydrogenase: Swivelling the dIII component may gate the proton channel

Jackson, J. B., Leung, J. H., Stout, C. D., Schurig-Briccio, L. A. & Gennis, R. B., Jul 20 2015, In : FEBS Letters. 589, 16, p. 2027-2033 7 p.

Research output: Contribution to journalReview article

Ribosomally synthesized and post-translationally modified peptide natural product discovery in the genomic era

Hetrick, K. J. & van der Donk, W. A., Jun 1 2017, In : Current Opinion in Chemical Biology. 38, p. 36-44 9 p.

Research output: Contribution to journalReview article

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Arnison, P. G., Bibb, M. J., Bierbaum, G., Bowers, A. A., Bugni, T. S., Bulaj, G., Camarero, J. A., Campopiano, D. J., Challis, G. L., Clardy, J., Cotter, P. D., Craik, D. J., Dawson, M., Dittmann, E., Donadio, S., Dorrestein, P. C., Entian, K. D., Fischbach, M. A., Garavelli, J. S., Göransson, U. & 45 others, Gruber, C. W., Haft, D. H., Hemscheidt, T. K., Hertweck, C., Hill, C., Horswill, A. R., Jaspars, M., Kelly, W. L., Klinman, J. P., Kuipers, O. P., Link, A. J., Liu, W., Marahiel, M. A., Mitchell, D. A., Moll, G. N., Moore, B. S., Müller, R., Nair, S. K., Nes, I. F., Norris, G. E., Olivera, B. M., Onaka, H., Patchett, M. L., Piel, J., Reaney, M. J. T., Rebuffat, S., Ross, R. P., Sahl, H. G., Schmidt, E. W., Selsted, M. E., Severinov, K., Shen, B., Sivonen, K., Smith, L., Stein, T., Süssmuth, R. D., Tagg, J. R., Tang, G. L., Truman, A. W., Vederas, J. C., Walsh, C. T., Walton, J. D., Wenzel, S. C., Willey, J. M. & Van Der Donk, W. A., Jan 2013, In : Natural Product Reports. 30, 1, p. 108-160 53 p.

Research output: Contribution to journalReview article

Rings, radicals, and regeneration: The early years of a bioorganic laboratory

van der Donk, W. A., Dec 22 2006, In : Journal of Organic Chemistry. 71, 26, p. 9561-9571 11 p.

Research output: Contribution to journalReview article

RNA Gel Shift Assays for Analysis of Hormone Control of mRNA Stability

Dodson, R. E., Goolsby, K. M., Acena-Nagel, M., Mao, C. & Shapiro, D. J., Jan 1 2003, In : Methods in enzymology. 364, p. 350-361 12 p.

Research output: Contribution to journalReview article

RNA modifications and structures cooperate to guide RNA-protein interactions

Lewis, C. J. T., Pan, T. & Kalsotra, A., Mar 1 2017, In : Nature Reviews Molecular Cell Biology. 18, 3, p. 202-210 9 p.

Research output: Contribution to journalReview article

Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies

Stone, J. D. & Kranz, D. M., 2013, In : Frontiers in immunology. 4, AUG, Article 244.

Research output: Contribution to journalReview article

Role of the Helicobacter pylori-Induced inflammatory response in the development of gastric cancer

Lamb, A. & Chen, L. F., Mar 1 2013, In : Journal of Cellular Biochemistry. 114, 3, p. 491-497 7 p.

Research output: Contribution to journalReview article

Scalable molecular dynamics with NAMD

Phillips, J. C., Braun, R., Wang, W., Gumbart, J., Tajkhorshid, E., Villa, E., Chipot, C., Skeel, R. D., Kalé, L. & Schulten, K., Dec 2005, In : Journal of Computational Chemistry. 26, 16, p. 1781-1802 22 p.

Research output: Contribution to journalReview article

Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins

Kerr, D., Tietjen, G. T., Gong, Z., Tajkhorshid, E., Adams, E. J. & Lee, K. Y. C., Oct 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 10, p. 2126-2133 8 p.

Research output: Contribution to journalReview article

Shaping the nuclear action of NF-κB

Chen, L. F. & Greene, W. C., May 1 2004, In : Nature Reviews Molecular Cell Biology. 5, 5, p. 392-401 10 p.

Research output: Contribution to journalReview article

Single-particle cryo-EM studies of transmembrane proteins in SMA copolymer nanodiscs

Sun, C. & Gennis, R. B., Jul 2019, In : Chemistry and Physics of Lipids. 221, p. 114-119 6 p.

Research output: Contribution to journalReview article

Soluble T cell receptor Vβ domains engineered for high-affinity binding to staphylococcal or streptococcal superantigens

Sharma, P., Wang, N. & Kranz, D. M., Feb 13 2014, In : Toxins. 6, 2, p. 556-574 19 p.

Research output: Contribution to journalReview article

Spectroscopic features of cytochrome P450 reaction intermediates

Luthra, A., Denisov, I. G. & Sligar, S. G., Mar 1 2011, In : Archives of Biochemistry and Biophysics. 507, 1, p. 26-35 10 p.

Research output: Contribution to journalReview article

Structural aspects of interactions within the Myc/Max/Mad network

Nair, S. K. & Burley, S. K., Feb 27 2006, In : Current Topics in Microbiology and Immunology. 302, p. 123-143 21 p.

Research output: Contribution to journalReview article

Structure and chemistry of cytochrome P450

Denisov, I. G., Makris, T. M., Sligar, S. G. & Schlichting, I., Jun 1 2005, In : Chemical reviews. 105, 6, p. 2253-2277 25 p.

Research output: Contribution to journalReview article

Structure and mechanism of lanthipeptide biosynthetic enzymes

van der Donk, W. A. & Nair, S. K., Dec 1 2014, In : Current Opinion in Structural Biology. 29, p. 58-66 9 p.

Research output: Contribution to journalReview article

Substrate activation by iron superoxo intermediates

van der Donk, W. A., Krebs, C. & Bollinger, J. M., Dec 1 2010, In : Current Opinion in Structural Biology. 20, 6, p. 673-683 11 p.

Research output: Contribution to journalReview article

Synthesis of the α,ω-dicarboxylic acid precursor of biotin by the canonical fatty acid biosynthetic pathway

Cronan, J. E. & Lin, S., Jun 1 2011, In : Current Opinion in Chemical Biology. 15, 3, p. 407-413 7 p.

Research output: Contribution to journalReview article

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

Stone, J. D., Chervin, A. S. & Kranz, D. M., Feb 1 2009, In : Immunology. 126, 2, p. 165-176 12 p.

Research output: Contribution to journalReview article

TCR affinity for p/MHC formed by tumor antigens that are self-proteins: Impact on efficacy and toxicity

Stone, J. D., Harris, D. T. & Kranz, D. M., Apr 1 2015, In : Current Opinion in Immunology. 33, p. 16-22 7 p.

Research output: Contribution to journalReview article

TCRs with high affinity for foreign pMHC show self-reactivity

Holler, P. D., Chlewicki, L. K. & Kranz, D. M., Jan 1 2003, In : Nature Immunology. 4, 1, p. 55-62 8 p.

Research output: Contribution to journalReview article

Teaching target-oriented and diversity-oriented organic synthesis at Harvard University

Burke, M. D. & Lalic, G., Jun 17 2002, In : Chemistry and Biology. 9, 5, p. 535-541 7 p.

Research output: Contribution to journalReview article

The balance between pre- and post-transfer editing in tRNA synthetases

Martinis, S. A. & Boniecki, M. T., Jan 21 2010, In : FEBS Letters. 584, 2, p. 455-459 5 p.

Research output: Contribution to journalReview article

The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal

Cronan, J. E., Jun 1 2014, In : Biochemical Journal. 460, 2, p. 157-163 7 p.

Research output: Contribution to journalReview article

The cyclooxygenase reaction mechanism

van der Donk, W. A., Tsai, A. L. & Kulmacz, R. J., Dec 31 2002, In : Biochemistry. 41, 52, p. 15451-15458 8 p.

Research output: Contribution to journalReview article

The cytochrome bd respiratory oxygen reductases

Borisov, V. B., Gennis, R. B., Hemp, J. & Verkhovsky, M. I., Nov 1 2011, In : Biochimica et Biophysica Acta - Bioenergetics. 1807, 11, p. 1398-1413 16 p.

Research output: Contribution to journalReview article

The cytochrome oxidase superfamily of redox-driven proton pumps

Calhoun, M. W., Thomas, J. W. & Gennis, R. B., Aug 1994, In : Trends in Biochemical Sciences. 19, 8, p. 325-330 6 p.

Research output: Contribution to journalReview article

The enzymatic biotinylation of proteins: A post-translational modification of exceptional specificity

Chapman-Smith, A. & Cronan, J. E., Sep 1 1999, In : Trends in Biochemical Sciences. 24, 9, p. 359-363 5 p.

Research output: Contribution to journalReview article

The enzyme function initiative

Gerlt, J. A., Allen, K. N., Almo, S. C., Armstrong, R. N., Babbitt, P. C., Cronan, J. E., Dunaway-Mariano, D., Imker, H. J., Jacobson, M. P., Minor, W., Poulter, C. D., Raushel, F. M., Sali, A., Shoichet, B. K. & Sweedler, J. V., Nov 22 2011, In : Biochemistry. 50, 46, p. 9950-9962 13 p.

Research output: Contribution to journalReview article

The low barrier hydrogen bond in enzymatic catalysis

Cleland, W. W., Frey, P. A. & Gerlt, J. A., Oct 2 1998, In : Journal of Biological Chemistry. 273, 40, p. 25529-25532 4 p.

Research output: Contribution to journalReview article

The many roles of glutamate in metabolism

Walker, M. C. & van der Donk, W. A., Mar 1 2016, In : Journal of Industrial Microbiology and Biotechnology. 43, 2-3, p. 419-430 12 p.

Research output: Contribution to journalReview article

The mechanism of ABC transporters: General lessons from structural and functional studies of an antigenic peptide transporter

Procko, E., O'Mara, M. L., Drew Bennett, W. F., Peter Tieleman, D. & Gaudet, R., May 1 2009, In : FASEB Journal. 23, 5, p. 1287-1302 16 p.

Research output: Contribution to journalReview article

The Molecular Industrial Revolution: Automated Synthesis of Small Molecules

Trobe, M. & Burke, M. D., Apr 9 2018, In : Angewandte Chemie - International Edition. 57, 16, p. 4192-4214 23 p.

Research output: Contribution to journalReview article

The Participation of Regulatory Lipids in Vacuole Homotypic Fusion

Starr, M. L. & Fratti, R. A., Jun 2019, In : Trends in Biochemical Sciences. 44, 6, p. 546-554 9 p.

Research output: Contribution to journalReview article

The role of cytochrome P450 monooxygenases in plant-insect interactions

Schuler, M. A., Dec 1996, In : Plant physiology. 112, 4, p. 1411-1419 9 p.

Research output: Contribution to journalReview article

The status of high-valent metal oxo complexes in the P450 cytochromes

Makris, T. M., Koenig, K. V., Schlichting, I. & Sligar, S. G., Apr 1 2006, In : Journal of Inorganic Biochemistry. 100, 4, p. 507-518 12 p.

Research output: Contribution to journalReview article

Thirty years of microbial P450 monooxygenase research: Peroxo-heme intermediates - The central bus station in heme oxygenase catalysis

Sligar, S. G., Makris, T. M. & Denisov, I. G., Dec 9 2005, In : Biochemical and Biophysical Research Communications. 338, 1, p. 346-354 9 p.

Research output: Contribution to journalReview article

Tissue Factor: A Key Molecule in Hemostatic and Nonhemostatic Systems

Morrissey, J. H., Feb 2004, In : International Journal of Hematology. 79, 2, p. 103-108 6 p.

Research output: Contribution to journalReview article

Tissue factor and factor VIIa: Understanding the molecular mechanism

Morrissey, J. & Mackman, N., 2008, In : Thrombosis Research. 122, SUPPL.1, p. S1-S2

Research output: Contribution to journalReview article

Tissue factor as a proinflammatory agent

Bokarewa, M. I., Morrissey, J. H. & Tarkowski, A., May 13 2002, In : Arthritis Research. 4, 3, p. 190-195 6 p.

Research output: Contribution to journalReview article

Tissue factor regulation and gene organization.

Morrissey, J. H., Gregory, S. A., Mackman, N. & Edgington, T. S., Dec 1 1989, In : Oxford surveys on eukaryotic genes. 6, p. 67-84 18 p.

Research output: Contribution to journalReview article

Towards the generalized iterative synthesis of small molecules

Lehmann, J. W., Blair, D. J. & Burke, M. D., Jan 1 2018, In : Nature Reviews Chemistry. 2, 2, 0115.

Research output: Contribution to journalReview article

Transmembrane proton translocation by cytochrome c oxidase

Brändén, G., Gennis, R. B. & Brzezinski, P., Aug 1 2006, In : Biochimica et Biophysica Acta - Bioenergetics. 1757, 8, p. 1052-1063 12 p.

Research output: Contribution to journalReview article

Tyrosyl radical cofactors

Pesavento, R. P. & van der Donk, W. A., Jan 1 2001, In : Advances in Protein Chemistry. 58, p. 317-385 69 p.

Research output: Contribution to journalReview article

Understanding cooperativity in human P450 mediated drug-drug interactions

Sligar, S. G. & Denisov, I. G., Apr 1 2007, In : Drug Metabolism Reviews. 39, 2-3, p. 567-579 13 p.

Research output: Contribution to journalReview article

Understanding enzymic catalysis: The importance of short, strong hydrogen bonds

Gerlt, J. A., Kreevoy, M. M., Cleland, W. W. & Frey, P. A., Apr 1997, In : Chemistry and Biology. 4, 4, p. 259-267 9 p.

Research output: Contribution to journalReview article