Research Output 1967 2020

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Review article

2013 Scientific Sessions Sol Sherry Distinguished Lecture in Thrombosis Polyphosphate: A Novel Modulator of Hemostasis and Thrombosis

Smith, S. A. & Morrissey, J. H., Jun 27 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 6, p. 1298-1305 8 p.

Research output: Contribution to journalReview article

Polyphosphates
Polymethyl Methacrylate
Hemostasis
Thrombosis
Blood Coagulation

A bacterium that has three pathways to regulate membrane lipid fluidity

Cronan, J. E., Apr 1 2006, In : Molecular Microbiology. 60, 2, p. 256-259 4 p.

Research output: Contribution to journalReview article

Membrane Fluidity
Membrane Lipids
Unsaturated Fatty Acids
Bacteria
Bacillus subtilis

Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors

Harris, D. T. & Kranz, D. M., Mar 1 2016, In : Trends in Pharmacological Sciences. 37, 3, p. 220-230 11 p.

Research output: Contribution to journalReview article

Antigen Receptors
T-cells
Cell- and Tissue-Based Therapy
T-Cell Antigen Receptor
T-Lymphocytes
Transcriptome
Lenses
RNA
Polyadenylation
Data handling

Advances in synthesis of biotin and assembly of lipoic acid

Cronan, J. E., Dec 2018, In : Current Opinion in Chemical Biology. 47, p. 60-66 7 p.

Research output: Contribution to journalReview article

Thioctic Acid
Biotin
Methylation
Metabolism
Escherichia coli

Aminoacyl-tRNA synthetases: A new image for a classical family

Martinis, S. A., Plateau, P., Cavarelli, J. & Florentz, C., Jul 1999, In : Biochimie. 81, 7, p. 683-700 18 p.

Research output: Contribution to journalReview article

Amino Acyl-tRNA Synthetases
RNA
Aminoacylation
RNA Splicing
Enzymes

A model T-cell receptor system for studying memory T-cell development

Chen, J., Eisen, H. N. & Kranz, D. M., Mar 1 2003, In : Microbes and Infection. 5, 3, p. 233-240 8 p.

Research output: Contribution to journalReview article

T-Cell Antigen Receptor
T-Lymphocytes
Clone Cells
Peptides
Antigen Receptors

A novel type of allosteric regulation: Functional cooperativity in monomeric proteins

Denisov, I. G. & Sligar, S., Mar 15 2012, In : Archives of Biochemistry and Biophysics. 519, 2, p. 91-102 12 p.

Research output: Contribution to journalReview article

Allosteric Regulation
Cytochrome P-450 Enzyme System
Drug interactions
Xenobiotics
Heme

Anticipatory UPR Activation: A Protective Pathway and Target in Cancer

Shapiro, D. J., Livezey, M., Yu, L., Zheng, X. & Andruska, N., Oct 1 2016, In : Trends in Endocrinology and Metabolism. 27, 10, p. 731-741 11 p.

Research output: Contribution to journalReview article

Unfolded Protein Response
Neoplasms
Endoplasmic Reticulum Stress
Breast Neoplasms
Protein Unfolding

Applications of Optobiology in Intact Cells and Multicellular Organisms

Khamo, J. S., Krishnamurthy, V. V., Sharum, S. R., Mondal, P. & Zhang, K., Oct 13 2017, In : Journal of Molecular Biology. 429, 20, p. 2999-3017 19 p.

Research output: Contribution to journalReview article

Light
Cell Differentiation
Signal Transduction
Cell Proliferation
Apoptosis

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins

Nath, A., Atkins, W. M. & Sligar, S. G., Feb 27 2007, In : Biochemistry. 46, 8, p. 2059-2069 11 p.

Research output: Contribution to journalReview article

Phospholipids
Membrane Proteins
Membranes
Lipid bilayers
Lipid Bilayers

Arabidopsis cytochrome P450s through the looking glass: A window on plant biochemistry

Schuler, M. A., Duan, H., Bilgin, M. & Ali, S., Jun 1 2006, In : Phytochemistry Reviews. 5, 2-3, p. 205-237 33 p.

Research output: Contribution to journalReview article

plant biochemistry
Cytochromes
cytochromes
Arabidopsis
Biochemistry

A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion

Sparks, R. P., Arango, A. S., Starr, M. L., Aboff, Z. L., Hurst, L. R., Rivera-Kohr, D. A., Zhang, C., Harnden, K. A., Jenkins, J. L., Guida, W. C., Tajkhorshid, E. & Fratti, R. A., Jan 1 2019, In : Journal of Biological Chemistry. 294, 46, p. 17168-17185 18 p.

Research output: Contribution to journalReview article

Open Access
N-Ethylmaleimide-Sensitive Proteins
SNARE Proteins
Phosphatidic Acids
Vacuoles
Carrier Proteins

Bacillus subtilis chemotaxis: a deviation from the Escherichia coli paradigm

Bischoff, D. S. & Ordal, G. W., Jan 1992, In : Molecular Microbiology. 6, 1, p. 23-28 6 p.

Research output: Contribution to journalReview article

Chemotaxis
Bacillus subtilis
Methylation
Escherichia coli
Halobacterium salinarum

Bacterial fatty acid biosynthesis: Targets for antibacterial drug discovery

Campbell, J. W. & Cronan, J., Oct 29 2001, In : Annual review of microbiology. 55, p. 305-332 28 p.

Research output: Contribution to journalReview article

Drug Discovery
Fatty Acids
Pharmaceutical Preparations
Anti-Bacterial Agents
Bacteria

Bacterial Membrane Lipids: Where Do We Stand?

Cronan, J. E., Nov 20 2003, In : Annual review of microbiology. 57, p. 203-224 22 p.

Research output: Contribution to journalReview article

Membrane Lipids
Phospholipids
Protein Precursors
DNA Replication
Permeability

Binding energetics of T-cell receptors: Correlation with immunological consequences

Manning, T. C. & Kranz, D. M., Sep 1 1999, In : Immunology Today. 20, 9, p. 417-422 6 p.

Research output: Contribution to journalReview article

T-Cell Antigen Receptor

Biosynthesis and mode of action of lantibiotics

Chatterjee, C., Paul, M., Xie, L. & van der Donk, W. A., Feb 1 2005, In : Chemical reviews. 105, 2, p. 633-683 51 p.

Research output: Contribution to journalReview article

Bacteriocins
Biosynthesis
Nisin
Bioactivity
Genes

Biosynthesis of phosphonic and phosphinic acid natural products

Metcalf, W. W. & van der Donk, W. A., Jul 27 2009, In : Annual review of biochemistry. 78, p. 65-94 30 p.

Research output: Contribution to journalReview article

Phosphinic Acids
Biosynthesis
Biological Products
Biochemistry
Phosphorous Acids

Blood clotting reactions on nanoscale phospholipid bilayers

Morrissey, J. H., Pureza, V., Davis-Harrison, R. L., Sligar, S. G., Ohkubo, Y. Z. & Tajkhorshid, E., Aug 6 2008, In : Thrombosis Research. 122, SUPPL.1, p. S23-S26

Research output: Contribution to journalReview article

Blood Coagulation
Phospholipids
Phosphatidylserines
Factor VIIa
Membranes

Bromodomain and extraterminal proteins - A novel class of therapeutic targets in epigenetics

Chen, J. J., Zhao, X. L., Wang, Z. & Chen, L-F., Jan 1 2017, In : Yaoxue Xuebao. 52, 8, p. 1209-1215 7 p.

Research output: Contribution to journalReview article

Staphylococcal Protein A
Epigenomics
Proteins
Therapeutic Uses
Therapeutics

Cameo appearances of aminoacyl-tRNA in natural product biosynthesis

Ulrich, E. C. & van der Donk, W. A., Dec 1 2016, In : Current Opinion in Chemical Biology. 35, p. 29-36 8 p.

Research output: Contribution to journalReview article

Biosynthesis
Transfer RNA
Biological Products
Genes
Enzymes

Capturing functional motions of membrane channels and transporters with molecular dynamics simulation

Shaikh, S. A., Wen, P. C., Enkavi, G., Huang, Z. & Tajkhorshid, E., Dec 1 2010, In : Journal of Computational and Theoretical Nanoscience. 7, 12, p. 2481-2500 20 p.

Research output: Contribution to journalReview article

transporter
Membrane Transport Proteins
Ion Channels
Molecular Dynamics Simulation
Molecular dynamics

CD antigens 2001

Mason, D., André, P., Bensussan, A., Buckley, C., Civin, C., Clark, E., De Haas, M., Goyert, S., Hadam, M., Hart, D., Hǒrejší, V., Meuer, S., Morrissey, J., Schwartz-Albiez, R., Shaw, S., Simmons, D., Uguccioni, M., Van Der Schoot, E., Vivier, E. & Zola, H., Dec 21 2001, In : Journal of Leukocyte Biology. 70, 5, p. 685-690 6 p.

Research output: Contribution to journalReview article

CD Antigens
Education
Antibodies

CD antigens 2001

Mason, D., André, P., Bensussan, A., Buckley, C., Civin, C., Clark, E., De Haas, M., Goyert, S., Hadam, M., Hart, D., Hořejší, V., Meuer, S., Morrissey, J., Schwartz-Albiez, R., Shaw, S., Simmons, D., Uguccioni, M., Van Der Schoot, E., Vivier, E. & Zola, H., Aug 23 2001, In : Immunology. 103, 4, p. 401-406 6 p.

Research output: Contribution to journalReview article

CD antigens 2001

Mason, D., André, P., Bensussan, A., Buckley, C., Civin, C., Clark, E., De Haas, M., Goyert, S., Hadam, M., Hart, D., Hořejší, V., Meuer, S., Morrissey, J., Schwartz-Albiez, R., Shaw, S., Simmons, D., Uguccioni, M., Van Der Schoot, E., Vivier, E. & Zola, H., Jan 1 2001, In : International Immunology. 13, 9, p. 1095-1098 4 p.

Research output: Contribution to journalReview article

Chapter 11 Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs

Ritchie, T. K., Grinkova, Y. V., Bayburt, T. H., Denisov, I. G., Zolnerciks, J. K., Atkins, W. M. & Sligar, S. G., Dec 14 2009, In : Methods in enzymology. 464, C, p. 211-231 21 p.

Research output: Contribution to journalReview article

Phospholipids
Membrane Proteins
Membranes
Bacteriorhodopsins
Lipids

Characterization of Lipid-Protein Interactions and Lipid-Mediated Modulation of Membrane Protein Function through Molecular Simulation

Muller, M. P., Jiang, T., Sun, C., Lihan, M., Pant, S., Mahinthichaichan, P., Trifan, A. & Tajkhorshid, E., May 8 2019, In : Chemical reviews. 119, 9, p. 6086-6161 76 p.

Research output: Contribution to journalReview article

Membrane Proteins
Modulation
Lipids
Proteins
Molecular dynamics

Chemical and enzymatic synthesis of lanthionines

Paul, M. & van der Donk, W. A., Jan 1 2005, In : Mini-Reviews in Organic Chemistry. 2, 1, p. 23-37 15 p.

Research output: Contribution to journalReview article

Bacteriocins
Nisin
Peptides
Food Preservatives
Sulfides

Chemical Physics in Living Cells-using Light to Visualize and Control Intracellular Signal Transduction

Krishnamurthy, V. V. & Zhang, K., 2018, In : Chinese Journal of Chemical Physics. 31, 4, p. 375-392 18 p.

Research output: Contribution to journalReview article

Chemotaxis in Bacillus subtilis: How bacteria monitor environmental signals

Garrity, L. F. & Ordal, G. W., 1995, In : Pharmacology and Therapeutics. 68, 1, p. 87-104 18 p.

Research output: Contribution to journalReview article

Chemotaxis
Bacillus subtilis
Bacteria
Escherichia coli
Proteins

Closing in on complete pathways of biotin biosynthesis

Lin, S. & Cronan, J. E., Jun 1 2011, In : Molecular BioSystems. 7, 6, p. 1811-1821 11 p.

Research output: Contribution to journalReview article

Biotin
Bacillus subtilis
Escherichia coli
Coenzymes
Biosynthetic Pathways

Comparison of the properties of prostaglandin H synthase-1 and -2

Kulmacz, R. J., Van Der Donk, W. A. & Tsai, A. L., Sep 2003, In : Progress in Lipid Research. 42, 5, p. 377-404 28 p.

Research output: Contribution to journalReview article

Cyclooxygenase 1
Cyclooxygenase 2
Protein Isoforms
Prostaglandin-Endoperoxide Synthases
Biosynthesis

Computational characterization of structural dynamics underlying function in active membrane transporters

Li, J., Wen, P. C., Moradi, M. & Tajkhorshid, E., Apr 1 2015, In : Current Opinion in Structural Biology. 31, p. 96-105 10 p.

Research output: Contribution to journalReview article

Membrane Transport Proteins
Active Biological Transport
Molecular Dynamics Simulation
Hydrolysis
Adenosine Triphosphate

Computational Dissection of Membrane Transport at a Microscopic Level

Jiang, T., Wen, P. C., Trebesch, N., Zhao, Z., Pant, S., Kapoor, K., Shekhar, M. & Tajkhorshid, E., Jan 1 2019, (Accepted/In press) In : Trends in Biochemical Sciences.

Research output: Contribution to journalReview article

Dissection
Membrane Transport Proteins
Membranes
Molecular Dynamics Simulation
Computational methods

Cooperative properties of cytochromes P450

Denisov, I. G., Frank, D. J. & Sligar, S., Nov 1 2009, In : Pharmacology and Therapeutics. 124, 2, p. 151-167 17 p.

Research output: Contribution to journalReview article

Cytochrome P-450 Enzyme System
Xenobiotics
Aptitude
Enzymes
Mixed Function Oxygenases

Coupled proton and electron transfer reactions in cytochrome oxidase

Gennis, R. B., Jan 1 2004, In : Frontiers in Bioscience. 9, p. 581-591 11 p.

Research output: Contribution to journalReview article

Electron Transport Complex IV
Protons
Electrons
Membranes
Proton Pumps

Cyclopropane ring formation in membrane lipids of bacteria

Grogan, D. W. & Cronan, J. E., Dec 1 1997, In : Microbiology and Molecular Biology Reviews. 61, 4, p. 429-441 13 p.

Research output: Contribution to journalReview article

Membrane Lipids
Bacteria
Phospholipids
Unsaturated Fatty Acids
Enzymes

Cytochrome c oxidase: Exciting progress and remaining mysteries

Brzezinski, P. & Gennis, R. B., Oct 1 2008, In : Journal of Bioenergetics and Biomembranes. 40, 5, p. 521-531 11 p.

Research output: Contribution to journalReview article

Proton Pumps
Electron Transport Complex IV
Proton-Motive Force
Protons
Observation

Cytochrome P-450 and peroxidase chemistry.

Erman, J. E., Hager, L. P. & Sligar, S., 1994, In : Advances in inorganic biochemistry. 10, p. 71-118 48 p.

Research output: Contribution to journalReview article

Hemeproteins
Peroxidases
Cytochrome P-450 Enzyme System
Peroxidase
Oxidation-Reduction

Cytochromes P450 in nanodiscs

Denisov, I. G. & Sligar, S., Jan 1 2011, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1814, 1, p. 223-229 7 p.

Research output: Contribution to journalReview article

Cytochrome P-450 Enzyme System
Membranes
Kinetics
Viral Antigens
Biosynthesis

Developmental insights into the pathology of and therapeutic strategies for DM1: Back to the basics

Chau, A. & Kalsotra, A., Mar 1 2015, In : Developmental Dynamics. 244, 3, p. 377-390 14 p.

Research output: Contribution to journalReview article

Poisons
Trinucleotide Repeat Expansion
RNA
Fetal Proteins
Pathology

Development of Photoacoustic Probes for in Vivo Molecular Imaging

Reinhardt, C. J. & Chan, J., Jan 16 2018, In : Biochemistry. 57, 2, p. 194-199 6 p.

Research output: Contribution to journalReview article

Molecular imaging
Biological Models
Molecular Imaging
Photoacoustic effect
Optical Imaging

Discovery, biosynthesis, and engineering of lantipeptides

Knerr, P. J. & van der Donk, W. A., Jul 1 2012, In : Annual review of biochemistry. 81, p. 479-505 27 p.

Research output: Contribution to journalReview article

Bacterial Genomes
Biosynthesis
Gram-Positive Bacteria
Sulfides
Post Translational Protein Processing

Display, engineering, and applications of antigen-specific T cell receptors

Richman, S. A. & Kranz, D. M., Oct 1 2007, In : Biomolecular Engineering. 24, 4, p. 361-373 13 p.

Research output: Contribution to journalReview article

T-cells
Antigens
T-Cell Antigen Receptor
Display devices
Monoclonal Antibodies

Disproportionate impact of named reactions on chemical biology

Bearrood, T. E. & Chan, J. K. F., Jan 1 2017, In : Aldrichimica Acta. 50, 2, p. 31-41 11 p.

Research output: Contribution to journalReview article

Organic Chemistry

Divergent evolution of enzymatic function: Mechanistically diverse superfamilies and functionally distinct suprafamilies

Gerlt, J. A. & Babbitt, P. C., Jul 30 2001, In : Annual review of biochemistry. 70, p. 209-246 38 p.

Research output: Contribution to journalReview article

Protein Databases
Enzymes
Enoyl-CoA Hydratase
Amidohydrolases
Reaction intermediates

Diversity in chemotaxis mechanisms among the bacteria and archaea

Szurmant, H. & Ordal, G. W., Jun 1 2004, In : Microbiology and Molecular Biology Reviews. 68, 2, p. 301-319 19 p.

Research output: Contribution to journalReview article

Archaea
Chemotaxis
Bacillus subtilis
Escherichia coli
Bacteria

Diversity in enoyl-acyl carrier protein reductases

Massengo-Tiassé, R. P. & Cronan, J. E., Jan 1 2009, In : Cellular and Molecular Life Sciences. 66, 9, p. 1507-1517 11 p.

Research output: Contribution to journalReview article

Acyl Carrier Protein
Oxidoreductases
Triclosan
Isoniazid
Enzymes

DNA bending by nuclear receptors.

Nardulli, A. & Shapiro, D. J., Jan 1 1993, In : Receptor. 3, 4, p. 247-255 9 p.

Research output: Contribution to journalReview article

Cytoplasmic and Nuclear Receptors
Transcription
DNA
Response Elements
Estrogens