Biochemistry

Short survey

Acetoacetate decarboxylase: Hydrophobics, not electrostatics

Gerlt, J. A., Jul 2009, In : Nature chemical biology. 5, 7, p. 454-455 2 p.

Research output: Contribution to journal › Short survey

acetoacetate decarboxylase

X Ray Crystallography

Static Electricity

Catalytic Domain

A new role for estrogen receptor a in cell proliferation and cancer: Activating the anticipatory unfolded protein response

Livezey, M., Kim, J. E. & Shapiro, D. J., Jun 15 2018, In : Frontiers in Endocrinology. 9, JUN, 325.

Research output: Contribution to journal › Short survey

Unfolded Protein Response

Estrogen Receptors

Cell Proliferation

Neoplasms

Protein Folding

Avant Garde Fatty Acid Synthesis by Trypanosomes

Cronan, J. E., Aug 25 2006, In : Cell. 126, 4, p. 641-643 3 p.

Research output: Contribution to journal › Short survey

Trypanosoma brucei brucei

Trypanosomiasis

Fatty Acids

Essential Fatty Acids

Myristic Acid

Bacteria do it differently: An alternative path to squalene

Van Der Donk, W. A., May 27 2015, In : ACS Central Science. 1, 2, p. 64-65 2 p.

Research output: Contribution to journal › Short survey

Squalene

Bacteria

Barrels in pieces?

Gerlt, J. A. & Babbitt, P. C., Jan 19 2001, In : Nature Structural Biology. 8, 1, p. 5-7 3 p.

Research output: Contribution to journal › Short survey

Gene encoding

Gene Duplication

Fusion reactions

imidazole glycerol phosphate synthase

Bright Dyes Bring Biology into Focus

Yadav, A. K. & Chan, J., Sep 27 2017, In : ACS Central Science. 3, 9, p. 920-921 2 p.

Research output: Contribution to journal › Short survey

Dyes

Cas protein Cmr2 full of surprises

Huang, R. H., Mar 7 2012, In : Structure. 20, 3, p. 389-390 2 p.

Research output: Contribution to journal › Short survey

CRISPR-Cas Systems

RNA Stability

Proteins

Cytochrome c oxidase: One enzyme, two mechanisms?

Gennis, R. B., Jun 12 1998, In : Science. 280, 5370, p. 1712-1713 2 p.

Research output: Contribution to journal › Short survey

Paracoccus denitrificans

Chemical Models

Proton Pumps

Protein Conformation

Proton-Motive Force

Divergent evolution in enolase superfamily: Strategies for assigning functions

Gerlt, J. A., Babbitt, P. C., Jacobson, M. P. & Almo, S. C., Jan 2 2012, In : Journal of Biological Chemistry. 287, 1, p. 29-34 6 p.

Research output: Contribution to journal › Short survey

Protein Databases

Phosphopyruvate Hydratase

Proteins

Databases

"Fishing" for the functional proteome

Gerlt, J. A., Jan 1 2002, In : Nature Biotechnology. 20, 8, p. 786-787 2 p.

Research output: Contribution to journal › Short survey

Biological Phenomena

Proteome

Proteins

Flexible tetracycline synthesis yields promising antibiotics

Burke, M., Feb 6 2009, In : Nature chemical biology. 5, 2, p. 77-79 3 p.

Research output: Contribution to journal › Short survey

Tetracycline

Anti-Bacterial Agents

Biological Products

Bacteria

Glimpsing the critical intermediate in cytochrome P450 oxidations

Sligar, S., Nov 12 2010, In : Science. 330, 6006, p. 924-925 2 p.

Research output: Contribution to journal › Short survey

Cytochrome P-450 Enzyme System

Hydrogen

Carbon

Incompatible differences: View of an allogeneic pMHC-TCR complex

Kranz, D. M., Oct 2000, In : Nature Immunology. 1, 4, p. 277-278 2 p.

Research output: Contribution to journal › Short survey

Peptide T

T-Cell Antigen Receptor

T-Lymphocytes

Intracellular TLR signaling: A structural perspective on human disease

Lasker, M. V. & Nair, S. K., Jul 1 2006, In : Journal of Immunology. 177, 1, p. 11-16 6 p.

Research output: Contribution to journal › Short survey

Single Nucleotide Polymorphism

Communicable Diseases

Molecular Biology

Infection

Jekyll & Hyde: Evolution of a Superfamily

Martinis, S. A. & Joy Pang, Y. L., Dec 26 2007, In : Chemistry and Biology. 14, 12, p. 1307-1308 2 p.

Research output: Contribution to journal › Short survey

Tyrosine-tRNA Ligase

Cell signaling

Amino Acyl-tRNA Synthetases

Aminoacylation

Engineers

LE FACTEUR VII PLASMATIQUE ACTIVE EST-IL UN FACTEUR DE RISQUE CARDIOVASCULAIRE?

Translated title of the contribution: Activated factor VII in plasma: A risk factor for heart disease?Morrissey, J. H., Mar 1 1996, In : Sang Thrombose Vaisseaux. 8, 3, p. 146-151 6 p.

Research output: Contribution to journal › Short survey

Factor VIIa

Factor VII

Heart Diseases

Prospective Studies

Thromboplastin

Metalloproteins: The long and the short of it

Denisov, I. G. & Sligar, S. G., Aug 20 2015, In : Nature Chemistry. 7, 9, p. 687-688 2 p.

Research output: Contribution to journal › Short survey

Archaeal Proteins

Chloride Peroxidase

Metalloproteins

Sulfur

Cytochrome P-450 Enzyme System

New wine from old barrels

Gerlt, J. A., Mar 1 2000, In : Nature Structural Biology. 7, 3, p. 171-173 3 p.

Research output: Contribution to journal › Short survey

Indole-3-Glycerol-Phosphate Synthase

Wine

DNA Shuffling

Mutagenesis

Biosynthesis

One inositol ring to rule thrombosis

Morrissey, J. H., Aug 22 2013, In : Blood. 122, 8, p. 1331-1332 2 p.

Research output: Contribution to journal › Short survey

Polyphosphates

Inositol

Platelets

Hemostasis

Thrombosis

Physical map locations of genes encoding components of the aerobic respiratory chain of Escherichia coli

Calhoun, M. W., Newton, G. & Gennis, R. B., Jan 1 1991, In : Journal of bacteriology. 173, 5, p. 1569-1570 2 p.

Research output: Contribution to journal › Short survey

Cytochrome d Group

Aerobiosis

Gene Components

NADH Dehydrogenase

Bacterial Genes

Proton Dynamics at the Membrane Surface

Gennis, R. B., May 10 2016, In : Biophysical journal. 110, 9, p. 1909-1911 3 p.

Research output: Contribution to journal › Short survey

Protons

Membranes

Proton pump caught in the act

Gennis, R. B. & Ebrey, T. G., Oct 8 1999, In : Science. 286, 5438, p. 252-253 2 p.

Research output: Contribution to journal › Short survey

Halobacterium salinarum

Retinaldehyde

Secondary Protein Structure

Bacteriorhodopsins

Proton Pumps

Reconstituting bacterial RNA repair and modification in vitro

Chan, C. M., Zhou, C. & Huang, R. H., Oct 9 2009, In : Science. 326, 5950, 1 p.

Research output: Contribution to journal › Short survey

RNA, Transfer, Arg

RNA, Transfer, Asp

Protein Multimerization

Endoribonucleases

Bacterial RNA

Remarkable structural variation within fatty acid megasynthases

Cronan, J. E., May 2006, In : Nature chemical biology. 2, 5, p. 232-234 3 p.

Research output: Contribution to journal › Short survey

Fatty Acids

Ribotoxins Kill Cells by Chopping off the Head of tRNAs

Huang, R. H., Nov 5 2019, In : Structure. 27, 11, p. 1613-1614 2 p.

Research output: Contribution to journal › Short survey

Transfer RNA

Stem Cells

Small molecule inhibitors as probes for estrogen and androgen receptor action

Shapiro, D. J., Mao, C. & Cherian, M. T., Feb 11 2011, In : Journal of Biological Chemistry. 286, 6, p. 4043-4048 6 p.

Research output: Contribution to journal › Short survey

Androgen Receptors

Estrogen Receptors

Androgens

Estrogens

Molecules

Structure of cytochrome c oxidase, energy generator of aerobic life

Gennis, R. B. & Ferguson-Miller, S., Jan 1 1995, In : Science. 269, 5227, p. 1063-1064 2 p.

Research output: Contribution to journal › Short survey

Aerobiosis

Proton Pumps

X Ray Crystallography

Electron Transport Complex IV

Electron Transport

T Cells Use Rafts for Survival

Stone, J. D. & Kranz, D. M., Feb 26 2010, In : Immunity. 32, 2, p. 145-147 3 p.

Research output: Contribution to journal › Short survey

Peptide Receptors

Immunity

Homeostasis

Cytokines

Ligands

The diverse CheC-type phosphatases: Chemotaxis and beyond

Muff, T. J. & Ordal, G. W., Dec 1 2008, In : Molecular Microbiology. 70, 5, p. 1054-1061 8 p.

Research output: Contribution to journal › Short survey

Chemotaxis

Phosphoric Monoester Hydrolases

Bacillus subtilis

Euryarchaeota

Phosphoprotein Phosphatases

The E. coli bio operon: Transcriptional repression by an essential protein modification enzyme

Cronan, J. E., Aug 11 1989, In : Cell. 58, 3, p. 427-429 3 p.

Research output: Contribution to journal › Short survey

Gene expression regulation

Repressor Proteins

Bacterial Proteins

Biotin

Escherichia coli

The structure of mammalian fatty acid synthase turned back to front

Cronan, J. E., Dec 1 2004, In : Chemistry and Biology. 11, 12, p. 1601-1602 2 p.

Research output: Contribution to journal › Short survey

Type I Fatty Acid Synthase

Multifunctional Enzymes

Polyketide Synthases

Fatty Acid Synthases

Textbooks

The superfamily of heme-copper respiratory oxidases

Garcia-Horsman, J. A., Barquera, B., Rumbley, J., Ma, J. & Gennis, R. B., Jan 1 1994, In : Journal of bacteriology. 176, 18, p. 5587-5600 14 p.

Research output: Contribution to journal › Short survey

Molecular Sequence Data

Aerobic Bacteria

Protein Conformation

Electron Transport Complex IV

Heme

Understanding enzyme superfamilies. Chemistry as the fundamental determinant in the evolution of new catalytic activities

Babbitt, P. C. & Gerlt, J. A., Dec 5 1997, In : Journal of Biological Chemistry. 272, 49, p. 30591-30594 4 p.

Research output: Contribution to journal › Short survey

Catalyst activity

Enzymes

Scaffolds

Gene Duplication

Substrates