Research Output 1971 2019

Filter
Short survey
2018

A new role for estrogen receptor a in cell proliferation and cancer: Activating the anticipatory unfolded protein response

Livezey, M., Kim, J. E. & Shapiro, D. J., Jun 15 2018, In : Frontiers in Endocrinology. 9, JUN, 325.

Research output: Contribution to journalShort survey

Unfolded Protein Response
Estrogen Receptors
Cell Proliferation
Neoplasms
Protein Folding
2017

Bright Dyes Bring Biology into Focus

Yadav, A. K. & Chan, J. K. F., Sep 27 2017, In : ACS Central Science. 3, 9, p. 920-921 2 p.

Research output: Contribution to journalShort survey

Dyes
2016

Proton Dynamics at the Membrane Surface

Gennis, R. B., May 10 2016, In : Biophysical journal. 110, 9, p. 1909-1911 3 p.

Research output: Contribution to journalShort survey

Protons
Membranes
2015

Bacteria do it differently: An alternative path to squalene

van der Donk, W. A., May 27 2015, In : ACS Central Science. 1, 2, p. 64-65 2 p.

Research output: Contribution to journalShort survey

Bacteria

Metalloproteins: The long and the short of it

Denisov, I. G. & Sligar, S., Aug 20 2015, In : Nature Chemistry. 7, 9, p. 687-688 2 p.

Research output: Contribution to journalShort survey

Archaeal Proteins
Chloride Peroxidase
Metalloproteins
Sulfur
Cytochrome P-450 Enzyme System
2013

One inositol ring to rule thrombosis

Morrissey, J. H., Aug 22 2013, In : Blood. 122, 8, p. 1331-1332 2 p.

Research output: Contribution to journalShort survey

Polyphosphates
Inositol
Platelets
Hemostasis
Thrombosis
2012

Cas protein Cmr2 full of surprises

Huang, R. H., Mar 7 2012, In : Structure. 20, 3, p. 389-390 2 p.

Research output: Contribution to journalShort survey

CRISPR-Cas Systems
RNA Stability
Proteins

Divergent evolution in enolase superfamily: Strategies for assigning functions

Gerlt, J. A., Babbitt, P. C., Jacobson, M. P. & Almo, S. C., Jan 2 2012, In : Journal of Biological Chemistry. 287, 1, p. 29-34 6 p.

Research output: Contribution to journalShort survey

Protein Databases
Phosphopyruvate Hydratase
Proteins
Databases
2011

Small molecule inhibitors as probes for estrogen and androgen receptor action

Shapiro, D. J., Mao, C. & Cherian, M. T., Feb 11 2011, In : Journal of Biological Chemistry. 286, 6, p. 4043-4048 6 p.

Research output: Contribution to journalShort survey

Androgen Receptors
Estrogen Receptors
Androgens
Estrogens
Molecules
2010

Glimpsing the critical intermediate in cytochrome P450 oxidations

Sligar, S., Nov 12 2010, In : Science. 330, 6006, p. 924-925 2 p.

Research output: Contribution to journalShort survey

Cytochrome P-450 Enzyme System
Hydrogen
Carbon

T Cells Use Rafts for Survival

Stone, J. D. & Kranz, D. M., Feb 26 2010, In : Immunity. 32, 2, p. 145-147 3 p.

Research output: Contribution to journalShort survey

Peptide Receptors
Immunity
Homeostasis
Cytokines
Ligands
2009

Acetoacetate decarboxylase: Hydrophobics, not electrostatics

Gerlt, J. A., Jan 1 2009, In : Nature chemical biology. 5, 7, p. 454-455 2 p.

Research output: Contribution to journalShort survey

acetoacetate decarboxylase
X Ray Crystallography
Static Electricity
Catalytic Domain

Flexible tetracycline synthesis yields promising antibiotics

Burke, M., Feb 6 2009, In : Nature chemical biology. 5, 2, p. 77-79 3 p.

Research output: Contribution to journalShort survey

Tetracycline
Anti-Bacterial Agents
Biological Products
Bacteria

Reconstituting bacterial RNA repair and modification in vitro

Chan, C. M., Zhou, C. & Huang, R. H., Oct 9 2009, In : Science. 326, 5950, 1 p.

Research output: Contribution to journalShort survey

RNA, Transfer, Arg
RNA, Transfer, Asp
Protein Multimerization
Endoribonucleases
Bacterial RNA
2008

The diverse CheC-type phosphatases: Chemotaxis and beyond

Muff, T. J. & Ordal, G. W., Dec 1 2008, In : Molecular Microbiology. 70, 5, p. 1054-1061 8 p.

Research output: Contribution to journalShort survey

Chemotaxis
Phosphoric Monoester Hydrolases
Bacillus subtilis
Euryarchaeota
Phosphoprotein Phosphatases
2007

Jekyll & Hyde: Evolution of a Superfamily

Martinis, S. A. & Joy Pang, Y. L., Dec 26 2007, In : Chemistry and Biology. 14, 12, p. 1307-1308 2 p.

Research output: Contribution to journalShort survey

Tyrosine-tRNA Ligase
Cell signaling
Amino Acyl-tRNA Synthetases
Aminoacylation
Engineers
2006

Avant Garde Fatty Acid Synthesis by Trypanosomes

Cronan, J. E., Aug 25 2006, In : Cell. 126, 4, p. 641-643 3 p.

Research output: Contribution to journalShort survey

Trypanosoma brucei brucei
Trypanosomiasis
Fatty Acids
Essential Fatty Acids
Myristic Acid

Intracellular TLR signaling: A structural perspective on human disease

Lasker, M. V. & Nair, S. K., Jul 1 2006, In : Journal of Immunology. 177, 1, p. 11-16 6 p.

Research output: Contribution to journalShort survey

Single Nucleotide Polymorphism
Communicable Diseases
Molecular Biology
Infection

Remarkable structural variation within fatty acid megasynthases

Cronan, J. E., Jan 1 2006, In : Nature chemical biology. 2, 5, p. 232-234 3 p.

Research output: Contribution to journalShort survey

Fatty Acids
2004

The structure of mammalian fatty acid synthase turned back to front

Cronan, J. E., Dec 1 2004, In : Chemistry and Biology. 11, 12, p. 1601-1602 2 p.

Research output: Contribution to journalShort survey

Type I Fatty Acid Synthase
Multifunctional Enzymes
Polyketide Synthases
Fatty Acid Synthases
Textbooks
2002

"Fishing" for the functional proteome

Gerlt, J. A., Jan 1 2002, In : Nature Biotechnology. 20, 8, p. 786-787 2 p.

Research output: Contribution to journalShort survey

Biological Phenomena
Proteome
Proteins
2001

Barrels in pieces?

Gerlt, J. A. & Babbitt, P. C., Jan 19 2001, In : Nature Structural Biology. 8, 1, p. 5-7 3 p.

Research output: Contribution to journalShort survey

Gene encoding
Gene Duplication
Fusion reactions
imidazole glycerol phosphate synthase
2000

Incompatible differences: View of an allogeneic pMHC-TCR complex

Kranz, D. M., Jan 1 2000, In : Nature Immunology. 1, 4, p. 277-278 2 p.

Research output: Contribution to journalShort survey

Peptide T
T-Cell Antigen Receptor
T-Lymphocytes

New wine from old barrels

Gerlt, J. A., Mar 1 2000, In : Nature Structural Biology. 7, 3, p. 171-173 3 p.

Research output: Contribution to journalShort survey

Indole-3-Glycerol-Phosphate Synthase
Wine
DNA Shuffling
Mutagenesis
Biosynthesis
1999

Proton pump caught in the act

Gennis, R. B. & Ebrey, T. G., Oct 8 1999, In : Science. 286, 5438, p. 252-253 2 p.

Research output: Contribution to journalShort survey

Halobacterium salinarum
Retinaldehyde
Secondary Protein Structure
Bacteriorhodopsins
Proton Pumps
1998

Cytochrome c oxidase: One enzyme, two mechanisms?

Gennis, R. B., Jun 12 1998, In : Science. 280, 5370, p. 1712-1713 2 p.

Research output: Contribution to journalShort survey

Paracoccus denitrificans
Chemical Models
Proton Pumps
Protein Conformation
Proton-Motive Force
1997

Understanding enzyme superfamilies. Chemistry as the fundamental determinant in the evolution of new catalytic activities

Babbitt, P. C. & Gerlt, J. A., Dec 5 1997, In : Journal of Biological Chemistry. 272, 49, p. 30591-30594 4 p.

Research output: Contribution to journalShort survey

Catalyst activity
Enzymes
Scaffolds
Gene Duplication
Substrates
1996

LE FACTEUR VII PLASMATIQUE ACTIVE EST-IL UN FACTEUR DE RISQUE CARDIOVASCULAIRE?

Translated title of the contribution: Activated factor VII in plasma: A risk factor for heart disease?Morrissey, J. H., Mar 1 1996, In : Sang Thrombose Vaisseaux. 8, 3, p. 146-151 6 p.

Research output: Contribution to journalShort survey

Factor VIIa
Factor VII
Heart Diseases
Prospective Studies
Thromboplastin
1995

Structure of cytochrome c oxidase, energy generator of aerobic life

Gennis, R. B. & Ferguson-Miller, S., Jan 1 1995, In : Science. 269, 5227, p. 1063-1064 2 p.

Research output: Contribution to journalShort survey

Aerobiosis
Proton Pumps
X Ray Crystallography
Electron Transport Complex IV
Electron Transport
1994

The superfamily of heme-copper respiratory oxidases

Garcia-Horsman, J. A., Barquera, B., Rumbley, J., Ma, J. & Gennis, R. B., Jan 1 1994, In : Journal of bacteriology. 176, 18, p. 5587-5600 14 p.

Research output: Contribution to journalShort survey

Molecular Sequence Data
Aerobic Bacteria
Protein Conformation
Electron Transport Complex IV
Heme
1991

Physical map locations of genes encoding components of the aerobic respiratory chain of Escherichia coli

Calhoun, M. W., Newton, G. & Gennis, R. B., Jan 1 1991, In : Journal of bacteriology. 173, 5, p. 1569-1570 2 p.

Research output: Contribution to journalShort survey

Cytochrome d Group
Aerobiosis
Gene Components
NADH Dehydrogenase
Bacterial Genes
1989

The E. coli bio operon: Transcriptional repression by an essential protein modification enzyme

Cronan, J. E., Aug 11 1989, In : Cell. 58, 3, p. 427-429 3 p.

Research output: Contribution to journalShort survey

Gene expression regulation
Repressor Proteins
Bacterial Proteins
Biotin
Escherichia coli