Research Output 1968 2019

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Letter
2019

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

Coleman, J. A., Yang, D., Zhao, Z., Wen, P. C., Yoshioka, C., Tajkhorshid, E. & Gouaux, E., Jan 1 2019, In : Nature.

Research output: Contribution to journalLetter

Ibogaine
Serotonin Plasma Membrane Transport Proteins
Plasma Membrane Neurotransmitter Transport Proteins
Serotonin
Neurotransmitter Agents

Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia

Muraglia, K. A., Chorghade, R. S., Kim, B. R., Tang, X. X., Shah, V. S., Grillo, A. S., Daniels, P. N., Cioffi, A. G., Karp, P. H., Zhu, L., Welsh, M. J. & Burke, M. D., Mar 21 2019, In : Nature. 567, 7748, p. 405-408 4 p.

Research output: Contribution to journalLetter

Cystic Fibrosis Transmembrane Conductance Regulator
Ion Channels
Cystic Fibrosis
Amphotericin B
Epithelium
2018

Cytochrome b5 enhances androgen synthesis by rapidly reducing the CYP17A1 oxy-complex in the lyase step

Duggal, R., Denisov, I. G. & Sligar, S., Jul 2018, In : FEBS Letters. 592, 13, p. 2282-2288 7 p.

Research output: Contribution to journalLetter

Cytochromes b5
Lyases
Cytochrome P-450 Enzyme System
Androgens
NADPH-Ferrihemoprotein Reductase
2017

Silica particles contribute to the procoagulant activity of DNA and polyphosphate isolated using commercial kits

Smith, S. A., Baker, C. J., Gajsiewicz, J. M. & Morrissey, J. H., Jul 6 2017, In : Blood. 130, 1, p. 88-91 4 p.

Research output: Contribution to journalLetter

2014

Author response

Mishra, S., Verhalen, B., Stein, R. A., Wen, P. C., Tajkhorshid, E. & Mchaourab, H. S., May 16 2014, In : eLife. 2014, 3, e02740.

Research output: Contribution to journalLetter

2013

Influence of membrane composition on the enhancement of factor VIIa/tissue factor activity by magnesium ions

Tavoosi, N. & Morrissey, J. H., Nov 28 2013, In : Thrombosis and Haemostasis. 111, 4, p. 770-772 3 p.

Research output: Contribution to journalLetter

Blood Coagulation Tests
Cell Membrane Structures
Phosphatidylethanolamines
Factor VIIa
Thromboplastin
2012
Rhodobacter capsulatus
Rhodobacter sphaeroides
Bacterial Proteins
Electron Transport Complex IV
Protons
2010

Response: Strain-specific activation of NF-B by Helicobacter pylori CagA

Lamb, A., Li, J. D., Hatakeyama, M., Peek, R. M., Blanke, S. R. & Chen, L-F., Jan 1 2010, In : EMBO Reports. 11, 1, p. 11-12 2 p.

Research output: Contribution to journalLetter

Helicobacter pylori
2008

Changes to NIH grant system may backfire

Karp, P. D., Sherlock, G., Gerlt, J. A., Sim, I., Paulsen, I., Babbitt, P. C., Laderoute, K., Hunter, L., Sternberg, P., Wooley, J. & Bourne, P. E., Nov 21 2008, In : Science. 322, 5905, p. 1187-1188 2 p.

Research output: Contribution to journalLetter

Research Peer Review
Organized Financing
National Institutes of Health (U.S.)
Biomedical Research

Heparin is procoagulant in the absence of antithrombin

Smith, S. A. & Morrissey, J. H., Jul 1 2008, In : Thrombosis and Haemostasis. 100, 1, p. 160-162 3 p.

Research output: Contribution to journalLetter

Drug Dose Response Relationship
Heparin Cofactor II
Factor Va
Enoxaparin
Polyphosphates
2004

Complementarities and convergence of results in bacteriorhodopsin trimer simulations [2] (multiple letters)

Baudry, J., Tajkhorshid, E., Schultent, K., Kandt, C., Schlitter, J. & Gerwert, K., Aug 2004, In : Biophysical journal. 87, 2, p. 1394-1395 2 p.

Research output: Contribution to journalLetter

Chemical Models
Artificial Membranes
Bacteriorhodopsins
Protein Conformation
Molecular Models
2002

CD antigens 2002 [7]

Mason, D., André, P., Bensussan, A., Buckley, C., Civin, C., Clark, E., De Haas, M., Goyert, S., Hadam, M., Hart, D., Hořejší, V., Meuer, S., Morrissey, J. H., Schwartz-Albiez, R., Shaw, S., Simmons, D., Uguccioni, M., Der Schoot, E. V., Vivier, E. & Zola, H., May 15 2002, In : Blood. 99, 10, p. 3877-3880 4 p.

Research output: Contribution to journalLetter

2001

Phosphite dehydrogenase: An unusual phosphoryl transfer reaction

Vrtis, J. M., White, A. K., Metcalf, W. W. & van der Donk, W. A., Oct 3 2001, In : Journal of the American Chemical Society. 123, 11, p. 2672-2673 2 p.

Research output: Contribution to journalLetter

NADPH Oxidoreductases NADH
NAD
NAD phosphite oxidoreductase
Oxidoreductases

Structural characterization of a pentadienyl radical intermediate formed during catalysis by prostaglandin H synthase-2

Peng, S., Okeley, N. M., Tsai, A. L., Wu, G., Kulmacz, R. J. & van der Donk, W. A., Oct 2 2001, In : Journal of the American Chemical Society. 123, 15, p. 3609-3610 2 p.

Research output: Contribution to journalLetter

Isoenzymes
Electron spin resonance spectroscopy
Catalysis
Prostaglandin-Endoperoxide Synthases

The lesser "burden borne" by o-succinylbenzoate synthase: An "easy" reaction involving a carboxylate carbon acid [1]

Taylor, E. A., Palmer, D. R. J. & Gerlt, J. A., Oct 9 2001, In : Journal of the American Chemical Society. 123, 24, p. 5824-5825 2 p.

Research output: Contribution to journalLetter

Carboxylic acids
Thermodynamics
Carbon
Acids
Temperature
2000

Insights into the functional role of the tyrosine-histidine linkage in cytochrome c oxidase [17]

McCauley, K. M., Vrtis, J. M., Dupont, J. & van der Donk, W. A., Mar 15 2000, In : Journal of the American Chemical Society. 122, 10, p. 2403-2404 2 p.

Research output: Contribution to journalLetter

Electron Transport Complex IV
Histidine
Tyrosine

Mechanistic studies on the vitamin b12-catalyzed dechlorination of chlorinated alkenes

Shey, J. & van der Donk, W. A., Dec 13 2000, In : Journal of the American Chemical Society. 122, 49, p. 12403-12404 2 p.

Research output: Contribution to journalLetter

Dechlorination
Vitamins
Alkenes
Vitamin B 12
Olefins
1999

EPR and ENDOR of catalytic intermediates in cryoreduced native and mutant oxy-cytochromes P450cam: Mutation-induced changes in the proton delivery system [15]

Davydov, R., Macdonald, I. D. G., Makris, T. M., Sligar, S. & Hoffman, B. M., Nov 17 1999, In : Journal of the American Chemical Society. 121, 45, p. 10654-10655 2 p.

Research output: Contribution to journalLetter

Camphor 5-Monooxygenase
Electron Spin Resonance Spectroscopy
Cytochromes
Paramagnetic resonance
Protons
1993

Similar CO Binding Sites in Bacterial Cytochrome bo and Mammalian Cytochrome c Oxidase

Wang, J., Ching, Y. C., Rousseau, D. L., Hill, J. J., Rumbley, J. & Gennis, R. B., Apr 1 1993, In : Journal of the American Chemical Society. 115, 8, p. 3390-3391 2 p.

Research output: Contribution to journalLetter

Electron Transport Complex IV
Carbon Monoxide
Cytochromes
Binding Sites
1992

Catalytic Mechanism of Cytochrome P-450: Evidence for a Distal Charge Relay

Gerber, N. C. & Sligar, S., Oct 1 1992, In : Journal of the American Chemical Society. 114, 22, p. 8742-8743 2 p.

Research output: Contribution to journalLetter

1988

Reply from Morrissey and Edgington

Morrissey, J. H. & Edgington, T. S., Mar 11 1988, In : Cell. 52, 5, p. 639-640 2 p.

Research output: Contribution to journalLetter

1985
Hemeproteins
Free energy
Oxidation-Reduction
1976

Chemotactic repellents of Bacillus subtilis

Ordal, G. W. & Goldman, D. J., Jan 5 1976, In : Journal of Molecular Biology. 100, 1, p. 103-108 6 p.

Research output: Contribution to journalLetter

Bacillus subtilis
Membranes
Oxidative Phosphorylation
Enterobacteriaceae
Local Anesthetics

Origin of the Anomalous Soret Spectra of Carboxycytochrome P-450

Hanson, L. K., Eaton, W. A., Sligar, S., Gunsalus, I. C., Gouterman, M. & Connell, C. R., Apr 1 1976, In : Journal of the American Chemical Society. 98, 9, p. 2672-2674 3 p.

Research output: Contribution to journalLetter

Energy Transfer
Carbon Monoxide
Carbon monoxide
Energy transfer
Spectrum analysis