Data for "A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration-dependent manner."

  • Allison Y. Louie (Creator)
  • Laurie A Rund (Creator)
  • Karin A. Komiyama-Kasai (Creator)
  • Kelsie E. Weisenberger (Creator)
  • Kayla L. Stanke (Creator)
  • Ryan J. Larsen (Creator)
  • Brian J. Leyshon (Creator)
  • Matthew J. Kuchan (Creator)
  • Tapas Das (Creator)
  • Andrew Jonathan Steelman (Creator)

Dataset

Description

This dataset contains MRI data and Imaris modeling analysis of CLARITY-cleared, immunostained tissue associated with a study that assessed the effects of lipid blends containing various levels of a hydrolyzed fat system on myelin development in healthy neonatal piglets. Data are from thirty-two piglets of mixed sexes across four diet treatment groups and includes a sow-fed reference group. MRI data (presented in Figure 2 of the associated article) consists of volumetric data from Voxel-Based Morphometry analysis in brain grey matter and white matter, as well as mean fractional anisotropy and mean orientation dispersion index data from Tract-Based Spatial Statistics analysis. Imaris data (presented in Figure 3 of the associated article) consists of twenty-one select output measures from 3D modeling analysis of PLP-stained prefrontal cortex tissue. All methods used for collection/generation/processing of data are described in the associated article: Louie AY, Rund LA, Komiyama-Kasai KA, Weisenberger KE, Stanke KL, Larsen RJ, Leyshon BJ, Kuchan MJ, Das T, Steelman AJ. A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration-dependent manner. J Neurosci Res. 2023.
Date made availableOct 26 2023
PublisherUniversity of Illinois Urbana-Champaign

Keywords

  • myelin
  • Imaris
  • dietary lipid
  • diffusion tensor imaging
  • CLARITY
  • voxel-based morphometry
  • white matter

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